The Effects of a Whey Protein and Guar Gum-Containing Preload on Gastric Emptying, Glycaemia, Small Intestinal Absorption and Blood Pressure in Healthy Older Subjects
Abstract
:1. Introduction
2. Materials and Methods
2.1. Subjects
2.2. Protocol
2.3. Measurements
2.3.1. Gastric Emptying
2.3.2. Plasma Glucose and Insulin
2.3.3. Oral Glucose Absorption (Serum 3-OMG)
2.3.4. Superior Mesenteric Artery Blood Flow
2.3.5. Blood Pressure and Heart Rate
2.3.6. Cardiovascular Autonomic Nerve Dysfunction
2.4. Statistical Analysis
3. Results
3.1. Gastric Emptying
3.2. Plasma Glucose and Insulin
3.3. Glucose Absorption
3.4. Superior Mesenteric Artery Blood Flow
3.5. Blood Pressure and Heart Rate
3.5.1. Systolic Blood Pressure
3.5.2. Diastolic Blood Pressure
3.5.3. Heart Rate
3.6. Relationships between Plasma Insulin and Serum 3-OMG between the Two Study Days
4. Discussion
5. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Control (t = −3) | Preload (t = −18) | p Value | |
---|---|---|---|
SBP (mmHg) | 122.1 ± 3.2 | 120.0 ± 3.1 | 0.10 |
DBP (mmHg) | 68.2 ± 1.9 | 67.3 ± 1.9 | 0.38 |
HR (beats/min) | 62.1 ± 1.7 | 63.9 ± 2.3 | 0.09 |
Plasma glucose (mmol/L) | 5.2 ± 0.1 | 5.2 ± 0.1 | 0.68 |
Plasma insulin (mU/L) | 5.2 ± 0.9 | 5.3 ± 0.8 | 0.68 |
SMA blood flow (mL/min) | 344 ± 23.6 | 329 ± 24.8 | 0.34 |
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Pham, H.; Holen, I.S.; Phillips, L.K.; Hatzinikolas, S.; Huynh, L.Q.; Wu, T.; Hausken, T.; Rayner, C.K.; Horowitz, M.; Jones, K.L. The Effects of a Whey Protein and Guar Gum-Containing Preload on Gastric Emptying, Glycaemia, Small Intestinal Absorption and Blood Pressure in Healthy Older Subjects. Nutrients 2019, 11, 2666. https://doi.org/10.3390/nu11112666
Pham H, Holen IS, Phillips LK, Hatzinikolas S, Huynh LQ, Wu T, Hausken T, Rayner CK, Horowitz M, Jones KL. The Effects of a Whey Protein and Guar Gum-Containing Preload on Gastric Emptying, Glycaemia, Small Intestinal Absorption and Blood Pressure in Healthy Older Subjects. Nutrients. 2019; 11(11):2666. https://doi.org/10.3390/nu11112666
Chicago/Turabian StylePham, Hung, Iselin S. Holen, Liza K. Phillips, Seva Hatzinikolas, Lian Q. Huynh, Tongzhi Wu, Trygve Hausken, Christopher K. Rayner, Michael Horowitz, and Karen L. Jones. 2019. "The Effects of a Whey Protein and Guar Gum-Containing Preload on Gastric Emptying, Glycaemia, Small Intestinal Absorption and Blood Pressure in Healthy Older Subjects" Nutrients 11, no. 11: 2666. https://doi.org/10.3390/nu11112666