Beauvericin, a Bioactive Compound Produced by Fungi: A Short Review
Abstract
:1. Introduction
2. Bioactivity of Beauvericin
2.1. Insecticidal Activity
2.2. Antitumor Activity
Cell line | IC50 (μg/mL) | Reference |
---|---|---|
African green monkey kidney fibroblast Vero | 10 | [19] |
Human monocytic lymphoma cells U-937 | 24 | [21] |
Human breast cancer BC-1 | 15 | [19] |
Human breast cancer MCF-7 | 1.4 | [24] |
Human CNS cancer (glioma) SF-268 | 1.8 | [24] |
Human epidermoid carcinoma KB | >20 | [19] |
Human leukemia cell CCRF-CEM | 1–2 | [20] |
Human non-small cell lung cancer (NSCLC) A549 | 2.4–7.8 | [22] |
Human non-small cell lung cancer NCI-H460 | 1.1 | [24] |
Human pancreatic carcinoma MIA Pa Ca-2 | 1.3 | [24] |
Human promyelocytic leukemia HL-60 | 12 | [21] |
Human retinoblastoma Y79 | 0.4–4 | [25] |
2.3. Antimicrobial Activity
2.3.1. Antibacterial Activity
Gram-positive bacteria | Reference | Gram-negative bacteria | Reference |
---|---|---|---|
Bacillus spp. | [29,32] | Agrobacterium tumefaciens | [32] |
Bifidobacterium adolescentis | [29] | Escherichia coli CECT 4782 | [31] |
Clostridium perfringens | [29,31] | Escherichia coli | [32] |
Enterococcus faecium | [31] | Pseudomonas aeruginosa | [31] |
Eubaterium biforme | [29] | Pseudomonas lachrymans | [32] |
Listeria monocytogenes | [31] | Salmonella enterica | [31] |
Mycobacterium tuberculosis | [30] | Shigella dysenteriae | [31] |
Peptostreptococcus spp. | [29] | Xanthomonas vesicatoria | [32] |
Staphylococcu haemolyticus | [32] | Yersinia enterocolitica | [31] |
Paenibacillus spp. | [29] |
2.3.2. Antifungal Activity
3. Biosynthesis of Beauvericin
4. Production of Beauvericin by Fungal Fermentation
5. Perspectives
Acknowledgements
- Sample Availability: Beauvericin is available from the authors.
References and Notes
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Wang, Q.; Xu, L. Beauvericin, a Bioactive Compound Produced by Fungi: A Short Review. Molecules 2012, 17, 2367-2377. https://doi.org/10.3390/molecules17032367
Wang Q, Xu L. Beauvericin, a Bioactive Compound Produced by Fungi: A Short Review. Molecules. 2012; 17(3):2367-2377. https://doi.org/10.3390/molecules17032367
Chicago/Turabian StyleWang, Qinggui, and Lijian Xu. 2012. "Beauvericin, a Bioactive Compound Produced by Fungi: A Short Review" Molecules 17, no. 3: 2367-2377. https://doi.org/10.3390/molecules17032367