The Third Southern Cross Travel Medicine Conference (SCTMC 2018), which will be held at the Hilton Brisbane, Queensland, Australia, from 7-9 September 2018. The theme for this year’s conference is “Translating Knowledge into Practice Downunder”. SCTMC 2018 will build on a strong platform of professional development for health practitioners working in the field of travel medicine with stimulating, succinct and novel sessions covering a range of important travel and tropical medicine topics, including: A Changing Environment and Management of Malaria; Global Geography and Vaccine Preventable Disease – Including Rabies; the Safety and Security of Travellers; the Health of Special Traveller Populations; Controversies in Travel Health Practice; Management of Bugs, Bites and Stings; and Geographic Dermatology and its Impact Upon the Traveller. We will again be hosting the popular Yellow Fever Workshop on Saturday afternoon 8 September 2018.