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Toxics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Nano-Toxicity: Exploring the Ecotoxicological Impacts of Nanoparticles and Combined Exposures

edited by

Juan Wang

submission deadline 18 Sep 2025 | 1 articles | Viewed by 473 | Submission Open

Keywords: ecotoxicology; environmental toxicology; biological effects; nanoparticles; microplastics

(This special issue belongs to the Section Ecotoxicology)

Exposure to Chemicals and Health Effects in Occupational and Everyday Settings

edited by

Lidia Caporossi

and

Daniela Pigini

submission deadline 19 Sep 2025 | 5 articles | Viewed by 7341 | Submission Open

Keywords: chemicals; workplaces; workers; exposure; toxicity; methods; daily life

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Hazard Assessment of per- and Polyfluorinated Alkyl Sub-Stances (PFAS)

edited by

Tracey L. Woodlief

submission deadline 20 Sep 2025 | Viewed by 142 | Submission Open

Keywords: per- and polyfluorinated alkyl substances; PFAS; environmental impact; health effects; risk assessment methodologies; toxicological studies; environmental monitoring; hazard assessment; risk assessment; hazard assessment; risk assessment

(This special issue belongs to the Section Emerging Contaminants)

Cadmium Pollution and Occupational Exposure

edited by Yasushi Suwazono

submission deadline 26 Sep 2025 | 3 articles | Viewed by 4100 | Submission Open

Keywords: cadmium; environmental exposure; general population; occupational medicine; renal effect; mortality

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Classical Environmental Process Modeling, Interpretable Machine Learning, and Their Integrative Innovations—Targeting Atmospheric, Water, and Soil

edited by

and

submission deadline 26 Sep 2025 | 1 articles | Viewed by 1071 | Submission Open

Keywords: environmental models; environmental simulation; environmental management; machine learning; deep learning; source apportionment; atmosphere; soil; water

Endocrine-Disrupting Chemicals and Reproductive Toxicology

edited by

Michał Hubert Wróbel

submission deadline 30 Sep 2025 | 8 articles | Viewed by 14036 | Submission Open

Keywords: reproductive toxicology; endocrine disruptors; environmental pollutions; parabens; pesticides; plastic; phthalates; metals; polychlorinated biphenyls; polybrominated compounds

(This special issue belongs to the Section Reproductive and Developmental Toxicity)

The Toxicity of Heavy Metals and Chemical Pollutants in Agricultural Soil and Plants: Ecological Risks and Remediation

edited by

Peipei Song

submission deadline 30 Sep 2025 | 5 articles | Viewed by 9978 | Submission Open

Keywords: heavy metals; chemical pollutants; ecological risks; remediation; soil and plants; soil microorganisms; migration and transformation

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

PFAS Toxicology and Metabolism—2nd Edition

edited by

Denise MacMillan

William S. Baldwin

and

Subham Dasgupta

submission deadline 30 Sep 2025 | 6 articles | Viewed by 6226 | Submission Open

Keywords: PFAS; toxicity; metabolism; toxicokinetics; adverse outcomes; omics; biotransformation; biomonitoring; new approach methodologies (NAMs); non-targeted analysis (NTA)

(This special issue belongs to the Section Emerging Contaminants)

Antibiotics and Resistance Genes in Environment

edited by

Fengxia Yang

and Shimei Zheng

submission deadline 30 Sep 2025 | 3 articles | Viewed by 5097 | Submission Open

Keywords: antibiotics; antibiotic resistance genes; environmental fate; human health; ecosystem impact; risk assessment; mitigation strategies

(This special issue belongs to the Section Emerging Contaminants)

Computational Toxicology: Exposure and Assessment

edited by

Alla P. Toropova

submission deadline 30 Sep 2025 | 4 articles | Viewed by 2926 | Submission Open

Keywords: toxicology; mutagenicity; carcinogenicity; chronic toxicity; eco-toxicity; QSPR/QSAR; validation; risk assessment; new approach methodologies; artificial intelligence; Monte Carlo method; SMILES and quasi-SMILES; read across; mathematical toxicology; exposure

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Biomarkers of Oxidative Stress from Environmental and Occupational Exposure: Implications for Health Risk Assessment

edited by

Ata Rafiee

, Peter Sly and Mohammad Hoseini

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1575 | Submission Open

Keywords: biomarkers; human biomonitoring; health risk assessment; oxidative stress

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Health Effects of Air Pollution on Children and Adolescents

edited by Jing Li

submission deadline 30 Sep 2025 | 2 articles | Viewed by 1494 | Submission Open

Keywords: air pollution; health effects; PM2.5; ozone; nitrogen oxides; children; adolescents

(This special issue belongs to the Section Air Pollution and Health)

Application of In Vitro Toxicity Evaluation Models for Environmental Pollutants

edited by Leslimar Rios-Colon and Suzanne Compton Fitzpatrick

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1058 | Submission Open

Keywords: in vitro techniques; environmental contaminants; new approach methodologies (NAMSs); per- and polyfluoroalkyl substances (PFASs); microplastics; pesticides; endocrine-disrupting chemicals; complex in vitro models

Ecotoxicological Effects of Anthropogenic Contaminants in Aquatic Organisms

edited by

Chiara Maria Motta

Rosa Carotenuto

and

Chiara Fogliano

submission deadline 30 Sep 2025 | 1 articles | Viewed by 757 | Submission Open

Keywords: emerging pollutants; health assessment; aquatic ecosystems; behavioural alterations; histological alterations; gene expression; aquatic vertebrates and invertebrates; reproductive toxicology; interferences with metabolism

(This special issue belongs to the Section Ecotoxicology)

One Health, Many Risks: Ecotoxicology in the Age of Emerging Pollutants

edited by

Andrzej R. Reindl

, Maciej Tankiewicz and

Ewa Olkowska

submission deadline 30 Sep 2025 | Viewed by 276 | Submission Open

Keywords: One Health approach; ecotoxicology; environmental toxicology; hazardous organic pollutants; medical drugs in the environment; endocrine disruptors; chronic exposure pathways; genotoxicity markers; rare earth elements toxicity; VOC exposure in occupational settings

Drug Metabolism and Toxicological Mechanisms—2nd Edition

edited by Qi Wang,

Youbo Zhang

and

An Zhu

submission deadline 30 Sep 2025 | Viewed by 237 | Submission Open

Keywords: drug metabolism; toxicity; mechanism; preclinical study; clinical trial

(This special issue belongs to the Section Drugs Toxicity)

Effects of Exposure to Emerging Environmental Pollutants on Human Health

edited by Biban Gill,

Amith Maroli

, Kelsi Perttula and Lauren Petrick

submission deadline 30 Sep 2025 | Viewed by 225 | Submission Open

Keywords: persistent organic pollutants (POPs); emerging pollutants; environmental exposure; human Health epidemiology; omics; risk assessment; molecular epidemiology

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Air Pollution Monitoring and Epidemiology

edited by Liqiong Guo

submission deadline 30 Sep 2025 | Viewed by 208 | Submission Open

Keywords: air pollution monitoring; environmental epidemiology; health risk; exposure assessment; public health

Effects of Acute Exposure to Toxicants on Oxidative Stress in Aquatic Organisms, 2nd Edition

edited by

Luís Félix

submission deadline 30 Sep 2025 | Viewed by 139 | Submission Open

Keywords: toxicology; oxidative stress; antioxidant; biomarkers; reactive oxygen species; oxidative damage; redox homeostasis

(This special issue belongs to the Section Ecotoxicology)

Molecular Mechanisms of Disease Caused from Environmental Fluoride and Arsenic Exposures

edited by

Yanmei Yang

, Xiance Sun and

Dapeng Wang

submission deadline 15 Oct 2025 | 7 articles | Viewed by 8454 | Submission Open

Keywords: arsenic; fluorine; human health; toxicity effect; toxicity mechanism; biomarkers; risk assessment

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Novel Remediation Strategies for Soil Pollution

edited by Jiaqi Shi and Tingting Fan

submission deadline 15 Oct 2025 | 5 articles | Viewed by 6080 | Submission Open

Keywords: soil remediation; advanced oxidative process; soil risk assessment; bioremediation; combined remediation of soil and groundwater; development of innovative remediation material

(This special issue belongs to the Section Ecotoxicology)

Interventions, Practices, and Policies to Reduce Particulate Matter Air Pollution Exposure and Health Outcomes

edited by

Douglas Brugge

and Shir Ginzburg

submission deadline 15 Oct 2025 | Viewed by 163 | Submission Open

Keywords: exposure reduction; health outcomes; interventions; particulate matter; randomized trials

(This special issue belongs to the Section Air Pollution and Health)

Hazardous Effects of Pesticides on Human Health—2nd Edition

edited by

Balázs Ádám

Lode Godderis

and

Radu-Corneliu Duca

submission deadline 17 Oct 2025 | 2 articles | Viewed by 3898 | Submission Open

Keywords: pesticide; product formulation; chronic low-level exposure; comparative toxicological assessment; human health effect; genotoxicity; carcinogenicity; teratogenicity

(This special issue belongs to the Section Agrochemicals and Food Toxicology)

Soil Heavy Metal Pollution and Human Health

edited by

Ping Xiang

and Chengchen Wang

submission deadline 20 Oct 2025 | 3 articles | Viewed by 2382 | Submission Open

Keywords: heavy metals; human health; food safety; monitoring techniques; pretreatment methods; contaminant control approaches

(This special issue belongs to the Section Metals and Radioactive Substances)

Emerging Methodologies in Toxicology for Environmental Safety Assessment

edited by

Melissa Faria

Juliette Bedrossiantz

and

Marcelino Miguel Guedes de Jesus Oliveira

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1180 | Submission Open

Keywords: toxicology; chemical safety; emerging contaminants; integrated approaches; predictive modeling; new methodology approaches; high-throughput screening; adverse-outcome pathways; risk assessment; One Health

Ecological Remediation of Heavy Metal-Polluted Environment

edited by Ruyi Yang,

Yongjie Wang

and Meng Zhu

submission deadline 20 Oct 2025 | Viewed by 331 | Submission Open

Keywords: heavy metal pollution; ecological remediation; emerging techniques; rhizosphere microecological processes; remediation efficiency optimization; ecosystem health assessment post-remediation; remediation policies and standards

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Toxicological Effects of Natural Products Derived from Plants or Animals Used in Therapeutical Treatments

edited by

Laura Narciso

and Carla Raggi

submission deadline 24 Oct 2025 | Viewed by 204 | Submission Open

Keywords: natural products; plant; animal; therapeutic effect; toxicological evaluation; cytotoxicity; genotoxicity; reproductive toxicity

Genotoxicity of Environmental Pollutants: From Mechanistic Insights to Risk Assessment

edited by

Antonio Cascajosa-Lira

and

Remedios Guzmán-Guillén

submission deadline 24 Oct 2025 | Viewed by 117 | Submission Open

Keywords: mutagenicity; carcinogenicity; Ames; DNA damage; risk assessment; environmental pollutants; micronucleus

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Transformation Process and Toxic Effects of Pollutants in Agricultural Environment

edited by

Changbo Zhang

, Liang Peng and Weijie Xue

submission deadline 25 Oct 2025 | 6 articles | Viewed by 7688 | Submission Open

Keywords: heavy metal pollution; emerging contaminants; contamination remediation; contaminated farmland; ecotoxicological aspects of the agro-environment; microplastics; toxicity

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Exploring Toxicity, Metabolism, and Transformation of Organic Pollutants

edited by

Jianteng Sun

and

Xiaolong Yu

submission deadline 31 Oct 2025 | 4 articles | Viewed by 4943 | Submission Open

Keywords: emerging organic pollutants; soil pollution; migration and biotransformation; environmental occurrence; metabolism; bioaccumulation; transformation products

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Prenatal Chemical Exposure and Child Health Outcomes

edited by

Maria José Rosa

, Cecilia Alcala and Jamil Lane

submission deadline 31 Oct 2025 | 4 articles | Viewed by 4883 | Submission Open

Keywords: chemical exposure; children’ s health; birth outcomes; environmental mixtures; prenatal exposure

(This special issue belongs to the Section Reproductive and Developmental Toxicity)

Health Effects of Exposure to Environmental Pollutants—2nd Edition

edited by Guang Jia and

Zhangjian Chen

submission deadline 31 Oct 2025 | 4 articles | Viewed by 3205 | Submission Open

Keywords: toxic effects; toxic mechanism; biomarkers; multi-omics techniques; nanotoxicity; heavy metals

(This special issue belongs to the Section Human Toxicology and Epidemiology)

Characteristics, Sources, Occurrence and Toxicological Mechanisms of Environmental Pollutants in Aquatic Systems

edited by Desheng Pei and Panpan Jia

submission deadline 31 Oct 2025 | 2 articles | Viewed by 3126 | Submission Open

Keywords: aquatic systems; environmental pollutants; neurodevelopmental and developmental toxicity; animal models; exposure and detection methods; human health; molecular mechanisms

Biomonitoring of Toxic Elements and Emerging Pollutants

edited by

Miguel Motas Guzmán

, Pedro Andreo-Martínez and Juan Jose Ramos

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2880 | Submission Open

Keywords: environmental health risks; bioaccumulation; biomonitoring; ecotoxicity; emerging contaminants; one health; biological effect monitoring; laboratory tests and validation

(This special issue belongs to the Section Emerging Contaminants)

Microplastics in Atmospheric, Aquatic, and Soil Ecosystems: Occurrence, Impacts, and Innovations in Detection and Mitigation

edited by Jheng-Jie Jiang and Tetsuro Agusa

submission deadline 31 Oct 2025 | 1 articles | Viewed by 2516 | Submission Open

Keywords: microplastics; nanoplastics; atmospheric microplastics; aquatic ecosystems; soil microplastics; analytical techniques; ecotoxicology; human health; remediation strategies; policy implications

Environmental Contaminants and Human Health—2nd Edition

edited by Lin Xu, Penghui Li and Xingchen Zhao

submission deadline 31 Oct 2025 | 3 articles | Viewed by 2271 | Submission Open

Keywords: environmental contaminants; exposure; health effects; risk estimation; toxicological effect; food chain; microplastics; emerging pollutants; nanotoxicology

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Advances in Monitoring, Transformation and Ecological Risk Assessment of Pharmaceuticals and Personal Care Products in Aquatic Environments

edited by Haohan Yang and

Jun Wu

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1603 | Submission Open

Keywords: PPCPs; natural organic materials; micro/nanoplastics; bioavailability; ecological risk assessment; biological effects; transfromation and metabolic pathways

(This special issue belongs to the Section Emerging Contaminants)

Pollutants in Soil and Groundwater, Effects and Strategies for Comprehensive Risk Assessment

edited by

Zhongkang Yang

, Wenhan Cheng, Zhuding Chu and

Ruijuan Qu

submission deadline 31 Oct 2025 | 1 articles | Viewed by 872 | Submission Open

Keywords: soil and groundwater pollution; risk assessment; ecological and human health impacts; remediation strategies; emerging pollutants; environmental monitoring

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Pharmaceutical Pollutants: Environmental Fate, Risk Assessment and Sustainable Solutions

edited by Guixiang Zhang

submission deadline 31 Oct 2025 | 1 articles | Viewed by 866 | Submission Open

Keywords: pharmaceuticals; antibiotic resistance genes; soil; water; sediments; environmental fate; risk assessment; sustainable solutions

(This special issue belongs to the Section Emerging Contaminants)

Oxidative Degradation and Toxicity of Environmental Pollutants

edited by

Jianfei Sun

and

Bo Wei

submission deadline 31 Oct 2025 | 1 articles | Viewed by 730 | Submission Open

Keywords: oxidative degradation; toxicity; environmental pollutants; volatile organic compounds; reaction mechanisms; kinetics; advanced oxidation process

(This special issue belongs to the Section Emerging Contaminants)

Assessing Contaminants in Food: Dietary Exposure, Human Health Risks, and Emerging Challenges

edited by

Virgínia Cruz Fernandes

submission deadline 31 Oct 2025 | Viewed by 156 | Submission Open

Keywords: environmental exposure; toxic chemicals; emerging pollutants; micro(nano)plastics; analytical methods; biomonitoring; health risks; human health; One Health

(This special issue belongs to the Section Emerging Contaminants)

Nanomaterials Adsorption and Removal of Pollutants and Environmental Remediation

edited by Yinqing Zhang and

Jingzhen Wang

submission deadline 31 Oct 2025 | Viewed by 127 | Submission Open

Keywords: nanomaterials; pollutant adsorption; pollutant removal; environmental remediation; toxicity reduction

(This special issue belongs to the Section Toxicity Reduction and Environmental Remediation)

Effects and Mechanism of Endocrine Disruption and Reproductive Abnormality of Emerging Pollutant

edited by Liping Lu, Yu Han,

Shixuan Cui

and

Tingjie Zhan

submission deadline 31 Oct 2025 | Viewed by 125 | Submission Open

Keywords: environmental toxicology; endocrine disruption; molecular mechanism; emerging pollutants; nuclear receptor; computational toxicology

(This special issue belongs to the Section Reproductive and Developmental Toxicity)

Human Exposure and Computational Modeling of Persistent Organic Pollutants (POPs)

edited by

Deepika Deepika

and

Vikas Kumar

submission deadline 10 Nov 2025 | 1 articles | Viewed by 1123 | Submission Open

Keywords: human biomonitoring; computational modeling; OMICS analysis; risk assessment; mechanism of action; adverse outcome pathways; human health predictive modeling machine learning new approach methodology

(This special issue belongs to the Section Novel Methods in Toxicology Research)

Toxicity and Safety Assessment of Exposure to Heavy Metals

edited by

Cristina Carvalho

and

Michael Aschner

submission deadline 14 Nov 2025 | 3 articles | Viewed by 4058 | Submission Open

Keywords: human exposure to metals; environmental contamination; metals’ biogeochemistry; food metal contaminants; toxic effects of metals; metals’ mechanisms of toxicity; risk assessment; biomarkers; metallodrugs; metal ion chelators

(This special issue belongs to the Section Metals and Radioactive Substances)

From Low-Tier to Individual Effects of Emerging Pollutants: Integrative Approaches to Ecotoxicological Assessments—2nd Edition

edited by

Tiago Simoes

Hugo Monteiro

and

Nuno Ferreira

submission deadline 15 Nov 2025 | 2 articles | Viewed by 1629 | Submission Open

Keywords: biomarkers; ecotoxicology; emerging pollutants; biological effects; mode of action; integrative analysis; analytical methods; sub-lethal endpoints

(This special issue belongs to the Section Ecotoxicology)

Emerging Pollutants in the Air and Health Risks

edited by

Qi Zhao

and

Gongbo Chen

submission deadline 20 Nov 2025 | 4 articles | Viewed by 8100 | Submission Open

Keywords: emerging pollutants; air pollution; exposure assessment; risk assessment; novel methodologies; statistical modeling; toxic mechanisms

(This special issue belongs to the Section Exposome Analysis and Risk Assessment)

Toxicity Assessment and Safety Management of Nanomaterials

edited by

Guotao Peng

submission deadline 20 Nov 2025 | 3 articles | Viewed by 3074 | Submission Open

Keywords: nanotoxicology; engineered nanomaterials; micro- and nanoplastics; nano– bio interactions; biotransformation; structure– activity relationship; health risks

(This special issue belongs to the Section Emerging Contaminants)

Plant Responses to Heavy Metal

edited by Yanqun Zu

submission deadline 20 Nov 2025 | Viewed by 451 | Submission Open

Keywords: heavy metals; plant; soil pollution; phytoremediation; mechanism; regulation and control

New Insights into the Environmental Behaviour and Toxicity of Critical and Strategic Metals in Aquatic Ecosystems

edited by

Maikel Rosabal

, Séverine Le Faucheur and

Xu Yang

submission deadline 20 Nov 2025 | Viewed by 173 | Submission Open

Keywords: critical and strategic minerals (CSMs); environmental behavior; toxicological risk assessment; bioavailability and bioaccumulation; aquatic ecosystems; omics techniques

(This special issue belongs to the Section Metals and Radioactive Substances)

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