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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Medicine and Exercise for Wellbeing: Effective Diagnosis and Non-Pharmacological Treatment in Chronic Conditions and Pain

edited by

Pedro Miguel Forte

submission deadline 16 Jul 2025 | 3 articles | Viewed by 3879

Keywords: chronic pain; physical exercise; diagnosis; chronic conditions; pain management

(This special issue belongs to the Section Sports Medicine)

Keratoconus: Current Status and Prospects

edited by

Uxía Regueiro

and Isabel Lema

submission deadline 16 Jul 2025 | 3 articles | Viewed by 2557

Keywords: keratoconus; prevention; diagnostic; biomarker discovery; genetics; exposome; treatment; personalized medicine; major challenges; technological advances

(This special issue belongs to the Section Ophthalmology)

New Insights into Acute Care and Emergency Surgery

edited by Jacob Chen and Avi Benov

submission deadline 17 Jul 2025 | 6 articles | Viewed by 10142 | Submission Open

Keywords: trauma surgery; emergency surgery; acute care; anesthesia; ICU

(This special issue belongs to the Section General Surgery)

Stress, Rhythms Dysregulation and Bipolar Spectrum

edited by

Mauro Giovanni Carta

and

Giulia Cossu

submission deadline 20 Jul 2025 | 15 articles | Viewed by 26197 | Submission Open

Keywords: bipolar spectrum; neo-Kraepelinian tradition; dimensional approach; social rhythms; chronobiological rhythms

(This special issue belongs to the Section Mental Health)

New Insights into Infectious Skin and Mucosal Diseases

edited by

Giulia Ciccarese

Sebastiano Recalcati

and Astrid Herzum

submission deadline 20 Jul 2025 | 4 articles | Viewed by 6824 | Submission Open

Keywords: exanthem; latent viruses; infectious diseases; skin eruptions; sexually transmitted infections

(This special issue belongs to the Section Dermatology)

Advances in the Surgical Management of Gynecological Malignancies

edited by Laurentiu Pirtea and Răzvan Ştefan Ilina

submission deadline 20 Jul 2025 | 2 articles | Viewed by 5925 | Submission Open

Keywords: minimally invasive surgery; laparoscopy surgery; robotic-assisted surgery; gynecological malignancies

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Advances in Cardiac Imaging

edited by

Łukasz A. Małek

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4783 | Submission Open

Keywords: non-invasive imaging; heart; vessels; application; diagnosis; technique

(This special issue belongs to the Section Cardiology)

Clinical Diagnosis and Management of Neonatal Diseases

edited by Ayala Gover and

Arieh Riskin

submission deadline 20 Jul 2025 | 6 articles | Viewed by 3966 | Submission Open

Keywords: newborn; preterm; neonatal intensive care; low birth weight; point-of-care ultrasound; neonatal monitoring

(This special issue belongs to the Section Clinical Pediatrics)

New Advances in Cardiovascular Diseases: The Cutting Edge

edited by

Fabiana Lucà

submission deadline 20 Jul 2025 | 2 articles | Viewed by 2181 | Submission Open

Keywords: cardiovascular disease (CVD); preventive cardiology; cardiac pharmacology; coronary artery disease (CAD); heart failure (HF); atrial fibrillation (AF); supraventricular and ventricular arrhythmias

(This special issue belongs to the Section Cardiovascular Medicine)

Advances in Hypertension and Related Complications

edited by

Thenral Socrates

and

Thilo Burkard

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1963 | Submission Open

Keywords: hypertension; hypertensive disorders of pregnancy; antihypertensive therapy; resistant hypertension; dual endothelin receptor antagonist; renal denervation; cardiovascular risk; adherence; kidney disease; secondary hypertension

(This special issue belongs to the Section Cardiovascular Medicine)

Long COVID and Cardiovascular Health: Clinical Perspectives on Risk and Management

edited by Mariana Tudoran and

Cristina Tudoran

submission deadline 20 Jul 2025 | 2 articles | Viewed by 1468 | Submission Open

Keywords: long COVID; cardiovascular disease; long COVID therapy; management of long COVID; mechanisms of long COVID

(This special issue belongs to the Section Cardiovascular Medicine)

New Technologies in Neurosurgery: An Insight into the Future

edited by Ismail Zaed

submission deadline 23 Jul 2025 | Viewed by 325 | Submission Open

Keywords: neurosurgery; training; technology; augmented reality; virtual reality; robot

(This special issue belongs to the Section Clinical Neurology)

Future Trends in the Diagnosis and Management of Celiac Disease

edited by

Carolina Ciacci

and

Antonella Santonicola

submission deadline 24 Jul 2025 | 6 articles | Viewed by 5319 | Submission Open

Keywords: celiac disease; gluten; autoimmune disease; extraintestinal manifestations; serologic diagnosis; gluten-free diet

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Artificial Intelligence (AI)-Based Diagnosis in Clinical Practice

edited by

Takao Fujisawa

submission deadline 24 Jul 2025 | 3 articles | Viewed by 4650 | Submission Open

Keywords: artificial intelligence; AI; diagnosis; clinical medicine; practice

(This special issue belongs to the Section Epidemiology & Public Health)

Clinical Treatment of Refractory Full Thickness Macular Hole (FTMH)

edited by

Rino Frisina

submission deadline 24 Jul 2025 | 1 articles | Viewed by 715 | Submission Open

Keywords: refractory full thickness macular hole; pars plana vittectomy; internal limiting membrane; peeling; tamponade; flap

(This special issue belongs to the Section Ophthalmology)

Clinical Updates on Maternal Fetal Medicine

edited by

Misgav Rottenstreich

and

Roberta Granese

submission deadline 25 Jul 2025 | 8 articles | Viewed by 17267 | Submission Open

Keywords: diabetes in pregnancy; hypertension in pregnancy; cholestasis in pregnancy; endocrine disorder in pregnancy; sepsis in pregnancy

(This special issue belongs to the Section Obstetrics & Gynecology)

Gynecological Surgery: New Clinical Insights and Challenges

edited by Francesco Plotti

submission deadline 25 Jul 2025 | 10 articles | Viewed by 12280 | Submission Open

Keywords: minimally invasive surgery; urogynecologic surgery; complications; gynecologic oncology; robotic surgery; benign gynecologic surgery; vaginal surgery

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Debates in Minimally Invasive Glaucoma Surgery (MIGS)

edited by

Etsuo Chihara

submission deadline 25 Jul 2025 | 9 articles | Viewed by 9797 | Submission Open

Keywords: MIGS (minimally invasive glaucoma surgery); schlemm’ s canal opening surgery; trabeculotomy; trabeculectomy; collector channel; histology; intraocular pressure; surgical success

(This special issue belongs to the Section Ophthalmology)

Clinical Advances in Hemodialysis

edited by Maurizio Bossola

submission deadline 25 Jul 2025 | 8 articles | Viewed by 7902 | Submission Open

Keywords: hemodialysis; interdialytic weight gain; symptom burden and quality of life; impaired cognitive function; fatigue; dietary restrictions; depression; anxiety; frailty; polypharmacy

(This special issue belongs to the Section Nephrology & Urology)

Chronic Complications of Type 2 Diabetes: Prevalence, Prevention, and Management

edited by

Ilias Migdalis

submission deadline 25 Jul 2025 | 6 articles | Viewed by 5741 | Submission Open

Keywords: pathogenesis of diabetic complications; epidemiology of diabetic complications; diabetic retinopathy; diabetic chronic kidney disease; diabetes neuropathies; coronary heart disease; peripheral vascular disease; hypertension and dyslipidemia in diabetes

(This special issue belongs to the Section Endocrinology & Metabolism)

Clinical Perspectives in Trauma and Orthopedic Surgery

edited by

Francesca Veronesi

submission deadline 25 Jul 2025 | 4 articles | Viewed by 5304 | Submission Open

Keywords: trauma; sports; ankle; knee; hip; cartilage regeneration; bone regeneration; orthopedic surgery

(This special issue belongs to the Section Orthopedics)

Thoracic Imaging in Cardiovascular and Pulmonary Disease Diagnosis

edited by Marco Sperandeo and

Carla Maria Irene Quarato

submission deadline 25 Jul 2025 | 3 articles | Viewed by 4763 | Submission Open

Keywords: thoracic imaging; cardiovascular diagnosis; pulmonary disease; clinical medicine; diagnostic accuracy; imaging techniques; thoracic ultrasound; patient care

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Foot and Ankle Surgery: State of the Art and Future Perspectives

edited by Sung Jae Kim and Jaehwang Song

submission deadline 25 Jul 2025 | 5 articles | Viewed by 4281 | Submission Open

Keywords: foot and ankle surgery; hallux disorders; lesser toe problem; diabetic foot salvage; calcaneal fracture; pilon fracture; ligament disorder

(This special issue belongs to the Section Orthopedics)

Multiple Myeloma: Advances in Diagnosis and Treatment

edited by

Martina Kleber

submission deadline 25 Jul 2025 | 2 articles | Viewed by 3238 | Submission Open

Keywords: multiple myeloma; early intervention; novel therapies; treatment approach; prognosis; bispecific antibodies; CAR T-cells

(This special issue belongs to the Section Oncology)

Applied Cardiorespiratory Physiology in Critical Care Medicine

edited by

Athanasios Chalkias

and Paraskevi Tselioti

submission deadline 25 Jul 2025 | 1 articles | Viewed by 3190 | Submission Open

Keywords: applied physiology; critical care medicine; cardiovascular physiology; respiratory physiology

(This special issue belongs to the Section Anesthesiology)

Vasculitis in Adults and Children: Symptoms, Diagnosis and Treatment—2nd Edition

edited by

Ryu Watanabe

submission deadline 25 Jul 2025 | 1 articles | Viewed by 2223 | Submission Open

Keywords: vasculitis; glucocorticoids; cyclophosphamide; molecularly targeted therapy; unmet clinical needs; potential therapeutic targets

(This special issue belongs to the Section Vascular Medicine)

Innovative Clinical Approaches in Oral Health Prevention and Management

edited by

Giulia Orilisi

Rossana Izzetti

and Flavia Vitiello

submission deadline 25 Jul 2025 | 2 articles | Viewed by 1979 | Submission Open

Keywords: oral health; oral prevention; teeth remineralization; oral pathology; oral health management; preventive dentistry; translational dentistry

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Accelerating Fracture Healing: Clinical Diagnosis and Treatment

edited by Seong-Eun Byun

submission deadline 25 Jul 2025 | 3 articles | Viewed by 1938 | Submission Open

Keywords: fracture; fracture surgery; fracture healing; diagnosis; treatment

(This special issue belongs to the Section Orthopedics)

Clinical Updates in Cardiac Electrophysiology: 2nd Edition

edited by Kenneth C. Bilchick

submission deadline 25 Jul 2025 | 1 articles | Viewed by 1718 | Submission Open

Keywords: arrhythmias; atrial fibrillation; cardiac electrophysiology; heart rhythm disorders; ablation; ventricular tachycardia; remote monitoring; digital health; artificial intelligence; cardiac magnetic resonance

(This special issue belongs to the Section Cardiology)

Optimizing Present and Future Therapeutic Choices for Treatment and Management of Chronic Inflammatory Bowel Diseases—2nd Edition

edited by

Lorenzo Bertani

submission deadline 25 Jul 2025 | 1 articles | Viewed by 1375 | Submission Open

Keywords: Inflammatory Bowel Diseases(IBD); JAK inhibitors; mucosal healing

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

The Role of Biomarkers in Cardiovascular Diseases

edited by Giorgia Panichella

submission deadline 25 Jul 2025 | 1 articles | Viewed by 978 | Submission Open

Keywords: biomarkers; cardiovascular diseases; heart failure; ischemic heart disease; cardiomyopathy; risk stratification; diagnosis; prognosis; inflammation

(This special issue belongs to the Section Cardiovascular Medicine)

New Clinical Treatment for Ocular Vascular Disease and Fundus Disease: Second Edition

edited by

Anna Karolina Nowińska

, Shohista Saidkasimova and

Slawomir Teper

submission deadline 25 Jul 2025 | 1 articles | Viewed by 843 | Submission Open

Keywords: ocular vascular diseases; fundus disorders; diabetic retinopathy; retinal vein occlusion; age-related macular degeneration; retinal detachment

(This special issue belongs to the Section Ophthalmology)

Interventional Cardiology—Challenges and Solutions

edited by

Yonggu Lee

submission deadline 25 Jul 2025 | 2 articles | Viewed by 789 | Submission Open

Keywords: chronic total occlusion; highly calcified coronary or lower extremity arteries; stentless percutaneous coronary intervention; chronic limb threatening ischemia; instent restenosis in the extremity artery diseases; endovascular therapy for pulmonary thromboembolism; transcatheter aortic valve replacemment for the bicuspid aortic valve; transcatheter aortic valve replacement for the valve-in-valve procedure; endovascular therapy for tricospid valve regurgitation; transcatheter edge-to-edge repair for mitral valve regurgitation

(This special issue belongs to the Section Cardiovascular Medicine)

Minimally Invasive Gynecological Surgery: State of the Art and the Perspectives

edited by Artur Jakimiuk

submission deadline 25 Jul 2025 | 1 articles | Viewed by 777 | Submission Open

Keywords: robotic surgery; laparoscopy; hysteroscopy; gynecological oncolgy surgery; minimally invasive gynecological procedures; reproductive endocrinology; urinary incontinence; endometriosis; advance laparoscopic surgery

(This special issue belongs to the Section Obstetrics & Gynecology)

Advances and Trends in Pediatric Surgery

edited by

Nikolaos Zavras

and

Anastasia Dimopoulou

submission deadline 25 Jul 2025 | 1 articles | Viewed by 755 | Submission Open

Keywords: pediatric surgery; minimally invasive surger; robotics; trends; advances

(This special issue belongs to the Section Clinical Pediatrics)

New Perspectives in Chronic Kidney Disease, Transplantation and Immune System

edited by

Maria Daoudaki

and Dimitrios A. Tsakiris

submission deadline 25 Jul 2025 | 1 articles | Viewed by 576 | Submission Open

Keywords: kidney transplantation; HLA; matching at the epitope level; DSAs; complement; kidney disease epigenetics; diabetic nephropathy; hemostasis; graft rejection; B and T cell immunophenotyping; end stage renal disease

(This special issue belongs to the Section Nephrology & Urology)

Hepatobiliary Surgery: State of the Art and Future Perspectives

edited by

Teresa Perra

and

Alberto Porcu

submission deadline 25 Jul 2025 | 1 articles | Viewed by 478 | Submission Open

Keywords: hepatobiliary surgery; cholangiocarcinoma; hepatocellular carcinoma; liver metastases; benign liver lesions

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in the Field of Cutaneous Malignancies: Background and Clinical Management

edited by

and

submission deadline 25 Jul 2025 | Viewed by 402 | Submission Open

Keywords: dermatology; skin cancer; diagnosis; melanoma; basal cell carcinoma; squamous cell carcinoma; imaging; artificial intelligence; dermoscopy; treatment

(This special issue belongs to the Section Dermatology)

Clinical Advances in Genetic Obesity and Health

edited by

Rena Kosti

and

Ioanna Panagiota Kalafati

submission deadline 25 Jul 2025 | Viewed by 361 | Submission Open

Keywords: obesity; genetics; health; nutrigenetics; clinical trials; personalized

(This special issue belongs to the Section Endocrinology & Metabolism)

Clinical Updates on Cardiac Electrophysiology

edited by Roberto Rordorf

submission deadline 25 Jul 2025 | Viewed by 194 | Submission Open

Keywords: percutaneous cardiac ablation; surgical cardiac ablation; atrial fibrillation; ventricula tachycardia; non invasive radiotherapy of cardiac arrhythmias; neuromodulation of cardiac arrhythmias

(This special issue belongs to the Section Cardiology)

Innovations in Coronary Artery Disease Treatment and Prevention

edited by

Jacek Bil

submission deadline 25 Jul 2025 | Viewed by 188 | Submission Open

Keywords: coronary artery disease (CAD); CAD prevention and treatment innovations; CAD biomarkers and imaging; advanced imaging and diagnostics; personalized medicine in cardiology; predictive analytics in CAD

(This special issue belongs to the Section Cardiovascular Medicine)

Robotic-Assisted Colorectal Surgery: Advancements and Clinical Applications

edited by

Giovanni Battista Levi Sandri

submission deadline 25 Jul 2025 | Viewed by 168 | Submission Open

Keywords: rectal cancer; diverticulitis; hemicolectomy; redo surgery; cost-effectiveness

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Advances in Hysteroscopic Technology for Gynecological Diseases

edited by Aya Mohr-Sasson and Raanan Meyer

submission deadline 25 Jul 2025 | Viewed by 160 | Submission Open

Keywords: diagnostic hysteroscopy; operative hysteroscopy; uterine sampling; uterine polyp; submucosal fibroid; hysteroscopic dilatation and curettage; hysteroscopic niche repair

(This special issue belongs to the Section Obstetrics & Gynecology)

Gestational Diabetes: Cutting-Edge Research and Clinical Practice

edited by Vendula Bartakova

submission deadline 26 Jul 2025 | 5 articles | Viewed by 3721 | Submission Open

Keywords: gestational diabetes mellitus; oral glucose tolerance test; treatment; pregnancy; peripartal outcomes

(This special issue belongs to the Section Endocrinology & Metabolism)

Research Progress and Challenges in Acute Abdominal Surgery

edited by Matteo Cimino

submission deadline 26 Jul 2025 | 1 articles | Viewed by 1717 | Submission Open

Keywords: acute abdominal emergencies; urgent surgical interventions; minimally invasive techniques; robotic surgery in emergency surgery; open surgery; complications; pain management; postoperative rehabilitation; acute appendicitis; acute biliary disease; intraoperative ultrasonography in emergency surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Cardiac Surgery: Innovations, Challenges and Opportunities

edited by Kyriakos Spiliopoulos and Keti Vitanova

submission deadline 28 Jul 2025 | 1 articles | Viewed by 593 | Submission Open

Keywords: minimally invasive cardiac surgery; redo cardiac surgery; transcatheter aortic valve implantation (TAVI); advances in mechanical circulatory support; endo-carditis; aortic surgery

(This special issue belongs to the Section Cardiology)

Peritoneal Dialysis—Procedure, Risks, Results

edited by

Božidar Vujičić

Bojan Knap

and

Robert Ekart

submission deadline 28 Jul 2025 | Viewed by 257 | Submission Open

Keywords: peritoneal dialysis; peritoneal catheter placement; peritoneal dialysis outcomes; peritoneal membrane; peritoneal transport; infectious complications; mechanical complications; nutritional status; volume management; peritoneal dialysis solutions

(This special issue belongs to the Section Nephrology & Urology)

Clinical Challenges and Advances in Oncology Radiology

edited by Ammar A Chaudhry

submission deadline 28 Jul 2025 | Viewed by 149 | Submission Open

Keywords: radiomics; theranostics; oncology; targeted therapies; immuno-oncology

(This special issue belongs to the Section Oncology)

Shoulder and Elbow Surgery: Clinical Updates and Perspectives

edited by Taku Hatta, Akihiko Hasegawa and Takuma Yuri

submission deadline 28 Jul 2025 | Viewed by 131 | Submission Open

Keywords: rotator cuff injuries; shoulder arthroplasty; elbow surgery; shoulder surgery; shoulder and elbow disease; arthroscopic surgery; orthopedic surgery

(This special issue belongs to the Section Orthopedics)

Innovations in Neurorehabilitation

edited by

Syoichi Tashiro

submission deadline 30 Jul 2025 | 8 articles | Viewed by 13316 | Submission Open

Keywords: clinical neurophysiology; neuroengineering; robotics; non-invasive transcranial brain stimulation; spinal stimulation; regenerative rehabilitation; neuroimaging; brain– computer interface; brain– spine interface; virtual reality; environmental control systems; higher level cognitive functions; vision rehabilitation

(This special issue belongs to the Section Clinical Rehabilitation)

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