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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current Trends in Vascular and Endovascular Surgery

edited by Karin Pfister and Fiona Rohlffs

submission deadline 15 Sep 2025 | 15 articles | Viewed by 21161

Keywords: vascular surgery; endovascular surgery; carotid endarterectomy; peripheral vascular diseases; vascular imaging; aortic diseases; aortic aneurysm; arteriovenous malformation; pelvic venous disorder; endovenous procedures; pal-liative therapy concept

(This special issue belongs to the Section Vascular Medicine)

Neuroimaging in 2024 and Beyond

edited by

Alberto Negro

and Lorenzo Ugga

submission deadline 15 Sep 2025 | 6 articles | Viewed by 12633

Keywords: neuroimaging; neuroradiology; neuro-oncology; brain degenerative disease; magnetic resonance imaging; neurosurgery; neurology

(This special issue belongs to the Section Clinical Neurology)

Emerging Technologies for Dental Imaging

edited by

Egon Burian

submission deadline 15 Sep 2025 | 6 articles | Viewed by 11696

Keywords: dental imaging; dental MRI; caries; periodontitis; orthodontics; oral surgery; craniomaxillofacial surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Antiphospholipid Syndrome: Clinical Advances in Diagnosis and Management

edited by Mattia Galli and

Alessandra Ida Celia

submission deadline 15 Sep 2025 | 5 articles | Viewed by 10686

Keywords: antiphospholipid syndrome; antiphospholipid antibodies; systemic lupus erythematosus; immunosuppressive therapy; diagnosis; management

(This special issue belongs to the Section Immunology & Rheumatology)

Foot and Ankle Surgery: Clinical Challenges and New Insights

edited by

Byung-Ki Cho

submission deadline 15 Sep 2025 | 5 articles | Viewed by 6733

Keywords: hallux valgus; minimally invasive correction; chronic ankle instability; arthroscopic Brostrom procedure; suture-tape augmentation; ankle arthritis; total ankle arthroplasty; ankle arthrodesis

(This special issue belongs to the Section Orthopedics)

Recent Advances in the Management of Fractures

edited by Giulio Maccauro and

Raffaele Vitiello

submission deadline 15 Sep 2025 | 3 articles | Viewed by 3980

Keywords: trauma; fractures; prosthesis; megaprosthesis; modular prosthesis; plate; nail; combo; screw; rehabilitation; radiology

(This special issue belongs to the Section Orthopedics)

New Trends in the Management of Periodontitis and Peri-Implantitis

edited by

João Botelho

submission deadline 15 Sep 2025 | 2 articles | Viewed by 2290

Keywords: periodontitis; periodontal disease; peri-implantitis; regenerative therapies; diagnostic markers; biomaterials; personalized medicine

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Recent Issues in Gynecologic Cancer Prevention and Screening

edited by

Taek Sang Lee

submission deadline 15 Sep 2025 | 1 articles | Viewed by 1768

Keywords: gynecologic cancer; prevention; screening

(This special issue belongs to the Section Oncology)

Current Challenges and Future Directions in Lung Resections in Thoracic Surgery

edited by Vasileios K. Kouritas and Emmanuel Michael Kefaloyannis

submission deadline 15 Sep 2025 | 1 articles | Viewed by 729

Keywords: robotic-assisted thoracic surgery (RATS); robotic; sublobar; 3D; emphysema; endobronchial valves; lung volume reduction surgery (LVRS); high-risk; AI; research; lung; screening; lung cancer

(This special issue belongs to the Section General Surgery)

Paradigm Changes in Cardiac Surgery and Interventional Cardiology

edited by

Miklos Bitay

submission deadline 15 Sep 2025 | 1 articles | Viewed by 618

Keywords: cardiac surgery; trans-catheter interventions; ischaemic heart disease; structural heart disease; electrophysiological interventions; state-of-the-art techniques; golden standards; therapeutic guidelines

(This special issue belongs to the Section Cardiology)

Advances in Breast Reconstruction: New Technologies Improving Clinical Outcomes

edited by Luigi Antonio Valdatta

submission deadline 18 Sep 2025 | 1 articles | Viewed by 1297 | Submission Open

Keywords: breast reconstruction; acellular dermal matrix (ADM); artificial intelligence in surgery; advanced prostheses; breast malformation correction; 3D printing in reconstruction; robotic-assisted breast surgery; regenerative surgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Clinical Advances in Kidney Transplantation

edited by Florin Ioan Elec and

Oana Antal

submission deadline 19 Sep 2025 | 3 articles | Viewed by 2697 | Submission Open

Keywords: kidney transplantation; immunosuppression; graft survival; donor risk assessment; post-transplant management; rejection and tolerance; precision medicine in transplantation

(This special issue belongs to the Section Nephrology & Urology)

Spine Surgery and Rehabilitation: Current Advances and Future Options

edited by Delia Cannizzaro

submission deadline 20 Sep 2025 | 13 articles | Viewed by 32462 | Submission Open

Keywords: spinal cord injury; neuronal plasticity; spinal surgery; spinal deformities; spinal tumors; motor rehabilitation; physical therapy modalities

(This special issue belongs to the Section Orthopedics)

Current Progress and Future Directions of Spine Surgery

edited by

Dong-Gune Chang

and Sam Yeol Chang

submission deadline 20 Sep 2025 | 15 articles | Viewed by 23087 | Submission Open

Keywords: minimally invasive surgery; navigation-assisted spine surgery; robotic-assisted spine surgery; deformity correction; spinal fusion; osteobiologic; surface technology; expandable cage; artificial intelligence; machine learning algorithms

(This special issue belongs to the Section Orthopedics)

Advances in Clinical Rheumatology

edited by

Jacopo Ciaffi

submission deadline 20 Sep 2025 | 12 articles | Viewed by 21632 | Submission Open

Keywords: rheumatoid arthritis; spondyloarthritis; interventional; osteoporosis; complex regional pain syndrome

(This special issue belongs to the Section Immunology & Rheumatology)

Musculoskeletal Infections: Clinical Diagnosis and Treatment

edited by

Kalliopi Alpantaki

and

Apostolos Karantanas

submission deadline 20 Sep 2025 | 8 articles | Viewed by 15856 | Submission Open

Keywords: computed tomography; magnetic resonance; musculoskeletal infections; septic arthritis; osteomyelitis; fungal infections; mycobacterium infections; prosthetic joint infections; postoperative infections; surgical treatment; VAC; hyperbaric oxygen

(This special issue belongs to the Section Orthopedics)

Obsessive Compulsive Disorder: Clinical Advances and Future Perspectives

edited by Andrea Fagiolini

submission deadline 20 Sep 2025 | 4 articles | Viewed by 13186 | Submission Open

Keywords: obsessions– compulsions; anxiety; OCD symptoms; treatment options; functional impairment

(This special issue belongs to the Section Mental Health)

New Insights into Glaucoma

edited by

Su-Ho Lim

and

Daniel Laroche

submission deadline 20 Sep 2025 | 9 articles | Viewed by 10563 | Submission Open

Keywords: glaucoma; intraocular pressure (IOP); risk calculators; glaucoma screening glaucoma surgery; cataract surgery; trabeculectomy; glaucoma drainage devices; minimally invasive glaucoma surgery (MIGS); artificial intelligence (AI)

(This special issue belongs to the Section Ophthalmology)

Clinical Innovations in Digestive Disease Diagnosis and Treatment

edited by

Stefano Rausei

and Angelo Benevento

submission deadline 20 Sep 2025 | 5 articles | Viewed by 9708 | Submission Open

Keywords: gastroenterology; digestive diseases; gastrointestinal endoscopy; upper GI surgery; colorectal surgery; hepatobiliary surgery; anastomotic leakage; gastrointestinal surgical oncology; inflammatory bowel disease; precision medicine in gastroenterology; minimally invasive gastrointestinal procedures; SIPAD congress contributions

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Current Trends in Implant Dentistry

edited by Marco Toia

submission deadline 20 Sep 2025 | 5 articles | Viewed by 9504 | Submission Open

Keywords: digital implant planning; osseointegration; guided surgery (static and dynamic); bone regeneration; zygomatic and pterygoid implants; 3D previsualization; craniofacial analysis; peri-implant diseases; immediate loading

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Risk Prediction for Gynecological Cancer

edited by

Federico Ferrari

submission deadline 20 Sep 2025 | 6 articles | Viewed by 8981 | Submission Open

Keywords: cervical cancer; endometrial cancer; tubo-ovarian cancer; diagnosis; treatment; prognosis

(This special issue belongs to the Section Obstetrics & Gynecology)

Perioperative Anesthesia: State of the Art and the Perspectives

edited by

Benedikt Preckel

submission deadline 20 Sep 2025 | 4 articles | Viewed by 8258 | Submission Open

Keywords: preoperative risk evaluation; prehabilitation; hemodynamic monitoring; post-surgical monitoring; patient deterioration; human factors; non-technical skills; cognitive aids; anesthetic drugs; regional anesthesia; healthcare worker wellness

(This special issue belongs to the Section Anesthesiology)

New Perspectives on the Diagnosis and Treatment of Liver Cirrhosis

edited by Elba Llop

submission deadline 20 Sep 2025 | 3 articles | Viewed by 7431 | Submission Open

Keywords: liver cirrhosis; portal hypertension; non-invasive diagnosis; elastography; gastro-esophagueal varices

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Updates and Perspectives on Subarachnoid Hemorrhage

edited by

Fusao Ikawa

submission deadline 20 Sep 2025 | 5 articles | Viewed by 7348 | Submission Open

Keywords: subarachnoid hemorrhage; outcome of subarachnoid hemorrhage; delayed cerebral ischemia; ; ruptured cerebral aneurysm; unruptured cerebral aneurysm; artificial intelligence; epidemiology

(This special issue belongs to the Section Clinical Neurology)

Clinical Management of Prosthetic Joint Infection (PJI)

edited by Daniel Pérez-Prieto

submission deadline 20 Sep 2025 | 5 articles | Viewed by 7274 | Submission Open

Keywords: prosthetic joint infection; debridement; biofilm; wound healing; multidisciplinary team; osteomyelitis

(This special issue belongs to the Section Orthopedics)

Advances in Stigma and Discrimination in Pediatric Mental Health

edited by

Clara González-Sanguino

and

Jairo Rodríguez-Medina

submission deadline 20 Sep 2025 | 3 articles | Viewed by 5751 | Submission Open

Keywords: stigma; discrimination; childhood; mental health; clinical psychology

(This special issue belongs to the Section Mental Health)

Catheter Ablation of Atrial Fibrillation: Advances and Challenges

edited by Nicholas Yick Loong Tan and Christopher V. DeSimone

submission deadline 20 Sep 2025 | 2 articles | Viewed by 5064 | Submission Open

Keywords: atrial fibrillation; catheter ablation; pulmonary vein isolation; cardiac electrophysiology; cardiac resynchronization therapy; pulsed field ablation; hybrid ablation; non-pulmonary vein triggers

(This special issue belongs to the Section Cardiology)

Advances in Scoliosis, Spinal Deformity, and Other Spinal Disorders: 2nd Edition

edited by

Zach Pennington

Daniel M. Sciubba

and

Benjamin D. Elder

submission deadline 20 Sep 2025 | 3 articles | Viewed by 4850 | Submission Open

Keywords: adult spinal deformity; scoliosis; spinal biomechanics; predictive calculators; bone health optimization; minimally invasive spine surgery; mechanical complication prevention; frailty

(This special issue belongs to the Section Orthopedics)

Clinical Advancements in Spine Surgery: Best Practices and Outcomes

edited by

Mitsuru Yagi

submission deadline 20 Sep 2025 | 5 articles | Viewed by 4407 | Submission Open

Keywords: adult spinal deformity; scoliosis; frailty; biological age; big data analysis

(This special issue belongs to the Section Orthopedics)

Corneal Diseases and Corneal Transplantation: Current Updates and Perspectives

edited by Itay Lavy and

Nir Erdinest

submission deadline 20 Sep 2025 | 5 articles | Viewed by 4246 | Submission Open

Keywords: corneal diseases; corneal transplantation; imaging techniques; pharmacological in-terventions; surgical interventions; tissue engineering

(This special issue belongs to the Section Ophthalmology)

Personalized Treatments for Glaucoma Patients

edited by Gloria Roberti

submission deadline 20 Sep 2025 | 3 articles | Viewed by 4032 | Submission Open

Keywords: glaucoma; intraocular pressure (IOP); optic nerve damage; visual field loss; ophthalmoscopy; angle closure glaucoma; open-angle glaucoma; primary glaucoma; secondary glaucoma; normal-tension glaucoma; pigmentary glaucoma

(This special issue belongs to the Section Ophthalmology)

Diabetic Nephropathy: Current Standards and Future Directions

edited by

Alaa S. Awad

Emaad M. Abdel-Rahman

and Charles W. Heilig

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2815 | Submission Open

Keywords: diabetic nephropathy: standard of care; diabetic nephropathy: future directions; SGLT2 in diabetic nephropathy; markers for diabetic nephropathy; diabetic nephropathy in the elderly; diabetic nephropathy in renal transplant patients; finerenone in diabetic nephropathy

(This special issue belongs to the Section Nephrology & Urology)

The Current State of Robotic Surgery in Urology

edited by

Luca Di Gianfrancesco

submission deadline 20 Sep 2025 | 3 articles | Viewed by 2234 | Submission Open

Keywords: robotic surgery; urology; surgical technique; multi-port; single port; major urological surgery; reconstructive surgery; robot-assisted radical cystectomy; patients’ selection

(This special issue belongs to the Section Nephrology & Urology)

Advances in the Diagnosis and Treatment of Acute Kidney Injury

edited by Gianpaolo Reboldi and

Mario Bonomini

submission deadline 20 Sep 2025 | 2 articles | Viewed by 2122 | Submission Open

Keywords: acute kidney injury; diagnosis; biomarkers; early detection; prognosis; renal replacement therapy

(This special issue belongs to the Section Nephrology & Urology)

Updates in the Orthopedic Management of Foot Disorders: 2nd Edition

edited by

Carlo Biz

and

Pietro Ruggieri

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1555 | Submission Open

Keywords: foot pathologies; diabetic feet; forefoot deformities; oncology surgery; foot tumors; minimally invasive surgery; percutaneous surgery; foot joint arthroscopy; stress fractures

(This special issue belongs to the Section Orthopedics)

Thoracic Surgery: State of the Art and Future Directions

edited by

Ugo Cioffi

and

Marco Scarci

submission deadline 20 Sep 2025 | 2 articles | Viewed by 1356 | Submission Open

Keywords: thoracic surgery; lung surgery; lung cancer; rib fractures; lung disease; pectus excavatum

(This special issue belongs to the Section Respiratory Medicine)

Foot Disorders: Multidisciplinary Perspectives on Prevention and Treatment

edited by Aksone L. Nouvong and Neil M. Paige

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1290 | Submission Open

Keywords: foot deformities; minimally invasive surgery; foot/ankle joint arthroscopy; nail pathology; trauma; neuropathy; Charcot arthropathy; melanoma; tendon injury; fractures; peripheral vascular disease; diabetic foot infections; diabetic foot ulcer; lower limb amputation

(This special issue belongs to the Section Orthopedics)

Recent Advances in the Prevention, Treatment, and Rehabilitation of Sports Injuries

edited by Nili Steinberg

submission deadline 20 Sep 2025 | 2 articles | Viewed by 1231 | Submission Open

Keywords: athletes; physical activity; sports; injuries; musculoskeletal; pain; rehabilitation; prevention; risk factors; functional abilities; muscle strength; joint range of motion (ROM); postural balance; ultrasonography maturation; adolescent

(This special issue belongs to the Section Sports Medicine)

Pancreatic Surgery: Clinical Practices and Challenges

edited by Guido Alsfasser and

Roberto Salvia

submission deadline 20 Sep 2025 | 1 articles | Viewed by 930 | Submission Open

Keywords: prognostic variables; surgical technique; outcome; timing of surgery; perioperative strategies; pancreatic cancer; pancreatitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in the Management of Intracranial Aneurysms

edited by Robert H. Rosenwasser, Nikolaos Mouchtouris and Elias Atallah

submission deadline 20 Sep 2025 | Viewed by 404 | Submission Open

Keywords: cerebral aneurysm; endovascular; open vascular; flow diversion; cerebral bypass; stent-assisted coiling

(This special issue belongs to the Section Clinical Neurology)

Liquid Biopsies in Oral Cancer: Advances and New Perspectives

edited by

Óscar Rapado-González

submission deadline 20 Sep 2025 | Viewed by 247 | Submission Open

Keywords: oral cancer; oral potentially malignant disorders; liquid biopsies; saliva and blood biomarkers; circulating tumor cells (CTCs); cell-free DNA (cfDNA)/circulating tumor DNA (ctDNA); cell-free RNA (cfRNA); extracellular vesicles (EVs); genetic and epigenetic biomarkers; early detection; prognosis and therapy response prediction; precision medicine

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Laparoscopic Surgery: Challenges and Solutions in Clinical Practice

edited by

Giuseppe Cavallaro

and Alessia Fassari

submission deadline 20 Sep 2025 | Viewed by 242 | Submission Open

Keywords: laparoscopic surgery; minimally invasive surgery; surgical challenges; clinical practice; surgical training; robotic-assisted surgery; artificial intelligence in surgery; laparoscopic instrumentation; intraoperative complications; surgical innovation; skill enhancement; surgical outcomes

(This special issue belongs to the Section General Surgery)

New Insights into the Management of Psoriasis and Cardiovascular Disease

edited by Amit Kumar Dey

submission deadline 20 Sep 2025 | Viewed by 152 | Submission Open

Keywords: psoriasis; psoriatic arthritis; inflammatory skin disease; chronic inflammation; cardiometabolic disease

(This special issue belongs to the Section Dermatology)

Aortic Aneurysms: Recent Advances in Diagnosis and Treatment

edited by Marco Virgilio Usai, Giuseppe Asciutto and Michele Piazza

submission deadline 23 Sep 2025 | 3 articles | Viewed by 3062 | Submission Open

Keywords: aortic aneurysms; abdominal aortic; thoraco-abdominal aortic aneurysms (TAAAs); complex aortic anatomies; endovascular abdominal aortic aneurysm repair (EVAR); endovascular thoracic aortic aneurysm repair (TEVAR); endovascular treatment

(This special issue belongs to the Section Cardiovascular Medicine)

New Insights into Minimally Invasive Vascular Surgery

edited by Ben Li and

Mohammad Qadura

submission deadline 23 Sep 2025 | 1 articles | Viewed by 854 | Submission Open

Keywords: minimally invasive vascular surgery; endovascular surgery; angioplasty; stenting; atherectomy; robotics; peripheral vascular intervention; carotid stenting; transcarotid artery revascularization; endovascular aneurysm repair

(This special issue belongs to the Section Vascular Medicine)

Hypertension: Clinical Treatment and Management

edited by

José L. Flores-Guerrero

submission deadline 24 Sep 2025 | 2 articles | Viewed by 1443 | Submission Open

Keywords: hypertension management; weight control; blood pressure monitoring; wearable technology; telemonitoring sys-tems; immune therapy; resistant hypertension; lifestyle interventions; cardiovascular health; advanced treatment strate-gies

(This special issue belongs to the Section Epidemiology & Public Health)

Clinical Perspectives in Stroke Rehabilitation

edited by Krystyna Jaracz,

Karolina Filipska-Blejder

and Robert Ślusarz

submission deadline 25 Sep 2025 | 8 articles | Viewed by 13716 | Submission Open

Keywords: stroke; clinical perspectives; therapy; functional outcome predictors; rehabilitation; quality of life

(This special issue belongs to the Section Clinical Rehabilitation)

Pancreatic Cancer: Current and Emerging Treatment Options

edited by Eleonora Lai,

Nicola Silvestris

and

Mario Scartozzi

submission deadline 25 Sep 2025 | 2 articles | Viewed by 12886 | Submission Open

Keywords: pancreatic cancer; treatment options; emerging therapies; precision medicine; immunotherapy; targeted therapy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Endocrine Tumors: Diagnosis, Treatment, and Management

edited by

Jules T. Zhang-Yin

Francesco Dondi

and Emmanouil Panagiotidis

submission deadline 25 Sep 2025 | 8 articles | Viewed by 12477 | Submission Open

Keywords: neuroendocrine tumors; thyroid cancer; adrenal gland tumors; pituitary adenomas; parathyroid tumors; pancreatic neuroendocrine tumors; surgical management; radiotherapy

(This special issue belongs to the Section Endocrinology & Metabolism)

Rehabilitation and Management of Stroke

edited by Thomas Platz

submission deadline 25 Sep 2025 | 6 articles | Viewed by 11950 | Submission Open

Keywords: stroke; rehabilitation; evidence; implementation; neurology; neurorehabilitation

(This special issue belongs to the Section Clinical Rehabilitation)

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