Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Pathogenesis, Diagnosis and Treatment of Cardiomyopathy and Cardiac Arrhythmias
edited by Sung Il Im
submission deadline 30 Sep 2025 | 6 articles | Viewed by 17658 | Submission Open
Keywords: arrhythmia; cardiomyopathy; pathogenesis; diagnosis
(This special issue belongs to the Section Molecular and Translational Medicine)
State-of-the-Art Drug Discovery and Development in Poland (2nd Edition) submission deadline 30 Sep 2025 | 8 articles | Viewed by 13842 | Submission Open
Keywords: in silico drug target profiling; drug delivery systems; drug– drug interactions; target-based screening; phenotypic screening; pharmaceutical modeling; computational chemistry; targeted therapy; biomarkers; bioimaging
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Advanced Research in Cardiovascular and Hemodynamic Monitoring
edited by and Scott T. Benken
submission deadline 30 Sep 2025 | 4 articles | Viewed by 11825 | Submission Open
Keywords: vasopressors; hemodynamic monitoring; hypotension; shock; cardiac arrest; heart rate; blood pressure; critical care; intensive care unit
(This special issue belongs to the Section Molecular and Translational Medicine)
Neurodevelopmental Disorders: From Pathophysiology to Novel Therapeutic Approaches—2nd Edition
edited by Nader Perroud and Markus Mathaus Kosel
submission deadline 30 Sep 2025 | 4 articles | Viewed by 9731 | Submission Open
Keywords: intellectual disability; autism spectrum disorder; attention-deficit/hyperactivity disorder; drug treatment; neuroimaging
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Pathogenesis, Diagnosis and Treatment of Hematologic Malignancies
edited by
submission deadline 30 Sep 2025 | 7 articles | Viewed by 9330 | Submission Open
Keywords: hematologic malignancies; pathogenesis; diagnosis; treatment; targeted therapy; molecular research
(This special issue belongs to the Section Molecular and Translational Medicine)
Ubiquitylation and Deubiquitylation in Health and Diseases
edited by Tadashi Nakagawa
submission deadline 30 Sep 2025 | 5 articles | Viewed by 8920 | Submission Open
Keywords: ubiquitin ligase; deubiquitinase; health; disease; therapeutics; eukaryotic cells
(This special issue belongs to the Section Molecular and Translational Medicine)
Pathogenesis, Diagnosis and Treatment of Cardiomyopathy and Cardiac Arrhythmias (2nd Edition)
edited by Sung Il Im
submission deadline 30 Sep 2025 | 7 articles | Viewed by 8441 | Submission Open
Keywords: arrhythmia; cardiomyopathy; pathogenesis; diagnosis
(This special issue belongs to the Section Molecular and Translational Medicine)
Cardiovascular Diseases in the Era of Precision Medicine submission deadline 30 Sep 2025 | 5 articles | Viewed by 7983 | Submission Open
Keywords: cardiology; precision medicine; cardiovascular diseases; genomics; proteomics; multi-omics; personalized therapy; diagnostic tools; imaging technologies; biosignals
(This special issue belongs to the Section Molecular and Translational Medicine)
Epigenetics and Metabolic Disorders
edited by Patrik Krumpolec
submission deadline 30 Sep 2025 | 3 articles | Viewed by 7960 | Submission Open
Keywords: metabolic diseases; epigenetics; DNA methylation; histone modification; non-coding RNA (ncRNA)-mediated gene regulation; heredity; environmental factors
(This special issue belongs to the Section Endocrinology and Metabolism Research)
State-of-the-Art Hepatic and Gastrointestinal Diseases in Germany
edited by
submission deadline 30 Sep 2025 | 7 articles | Viewed by 7775 | Submission Open
Keywords: biomarker; prevalence; Germany; inflammatory bowel disease; cancer
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Mechanisms and Treatment of Rheumatic Diseases
edited by Ruxandra Ionescu and
submission deadline 30 Sep 2025 | 3 articles | Viewed by 7193 | Submission Open
Keywords: rheumatology; immune-mediated rheumatic diseases; biologics; DMARDs; arthritis; lupus; vasculitis; spondyloarthritis; targets
(This special issue belongs to the Section Molecular and Translational Medicine)
Synaptic Function and Modulation in Health and Disease
edited by Jean-Marie C. Bouteiller
submission deadline 30 Sep 2025 | 4 articles | Viewed by 6967 | Submission Open
Keywords: synaptic function; synaptic plasticity; neurotransmitter release; receptor dynamics
(This special issue belongs to the Section Molecular and Translational Medicine)
Advancements in Lung Cancer Precision Oncology Research and Treatments
edited by , and Francesca Colonese
submission deadline 30 Sep 2025 | 5 articles | Viewed by 6713 | Submission Open
Keywords: lung; cancer; NSCLC; targeted therapies; immunotherapy; precision oncology; EGFR; KRAS; ALK; ROS1
(This special issue belongs to the Section Cancer Biology and Oncology)
The Role of NK Cells in Cancer Immunotherapy: Mechanisms, Evasion Strategies, and Therapeutic Advances
edited by Maria Eugenia Garcia Rubino
submission deadline 30 Sep 2025 | 1 articles | Viewed by 6351 | Submission Open
Keywords: NK cells; cancer immunotherapy; tumor evasion; cytotoxicity; CAR-NK; cytokines; IL-2; immunotherapy; tumor microenvironment
(This special issue belongs to the Section Cancer Biology and Oncology)
Latest Research in Post-COVID (Long COVID): Pathological and Treatment Studies of Sequelae and Complications—3rd Edition submission deadline 30 Sep 2025 | 6 articles | Viewed by 6312 | Submission Open
Keywords: COVID-19; long  COVID; pain; function; fatigue; dyspnoea; vaccine
(This special issue belongs to the Section Molecular and Translational Medicine)
An Update on Transplantation Immunology
edited by Hui-Yun Cheng
submission deadline 30 Sep 2025 | 4 articles | Viewed by 6255 | Submission Open
Keywords: transplantation; immunology; immunosuppression; immunomodulation
(This special issue belongs to the Section Immunology and Immunotherapy)
Molecular Characteristics of Cerebral Ischemia and Their Therapeutic Applications
edited by E-Jian Lee and Shengyang Huang
submission deadline 30 Sep 2025 | 3 articles | Viewed by 5826 | Submission Open
Keywords: cerebral ischemia; molecular mechanisms; pathophysiology; biomarkers; therapeutic strategies; neuroprotection; ischemic stroke; neuro-inflammation; translational research; neuroplasticity; neurophysiology; neuroscience; neuroelectrophysiology
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Pharmaceutical Treatments for Typical CKD Comorbidities submission deadline 30 Sep 2025 | 3 articles | Viewed by 5764 | Submission Open
Keywords: natural bioactive compounds; adjuvant treatment; protein energy wasting; mineral bone disorders; metabolic acidosis; hyperhomocysteinemia; uremic sarcopenia; PLADO diet; anemia in CKD
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Angiogenesis, Inflammation, and Oxidative Stress in Inflammatory Bowel Diseases
edited by and Dan Ionuț Gheonea
submission deadline 30 Sep 2025 | 3 articles | Viewed by 5734 | Submission Open
Keywords: inflammatory bowel disease; angiogenesis; inflammation; oxidative stress
(This special issue belongs to the Section Molecular and Translational Medicine)
Retinal Vascular Disorders: New Insights into Pathogenesis, Diagnosis and Treatment
edited by Irini P. Chatziralli
submission deadline 30 Sep 2025 | 2 articles | Viewed by 5271 | Submission Open
Keywords: diabetic retinopathy; retinal vein occlusion; retinal artery occlusion; sickle-cell retinopathy; optical coherence tomography; widefield imaging; OCT angiography
(This special issue belongs to the Section Molecular and Translational Medicine)
Pollutants and Human Health: Focus on Molecular-Level Research submission deadline 30 Sep 2025 | 1 articles | Viewed by 4431 | Submission Open
Keywords: environmental exposure; emerging pollutants; human and ecosystem health; environmental risk assessment; adverse outcome pathways; human risk assessment; endocrine-disrupting chemicals; cardiovascular endocrinology; neurovascular endocrinology; reproductive toxicology
(This special issue belongs to the Section Molecular and Translational Medicine)
The Treatment of Cardiovascular Diseases in the Critically Ill submission deadline 30 Sep 2025 | 4 articles | Viewed by 4310 | Submission Open
Keywords: septic cardiomyopathy; takotsubo syndrome; cardiac arrhythmias; acute coronary syndromes; antiplatelets; antithrombotics
(This special issue belongs to the Section Molecular and Translational Medicine)
The Art of ART (Assisted Reproductive Technologies) submission deadline 30 Sep 2025 | 4 articles | Viewed by 3802 | Submission Open
Keywords: assisted reproductive technologies; infertility diagnosis; intrauterine insemination (IUI); intracytoplasmic sperm injection (ICSI); in vitro fertilization (IVF); embryo implantation; oocyte quality; preimplantation genetic testing; mitochondrial replacement therapy; follicular recruitment; reproductive medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Organoid, Organ-on-Chip and Advanced 2D/3D Models for Human Tissue Engineering Applications
edited by
submission deadline 30 Sep 2025 | 3 articles | Viewed by 3784 | Submission Open
Keywords: organoid; organ-on-chip; 2D/3D model; tissue engineering; induced pluripotent stem cells; in vitro model
(This special issue belongs to the Section Biomedical Engineering and Materials)
Advancements in Neuroscience: A Special Issue in Honour of Ramón Y Cajal
edited by
submission deadline 30 Sep 2025 | 3 articles | Viewed by 3370 | Submission Open
Keywords: neurobiology; neuroscience; histology; imaging; nervous system; brain; neurodegenerative diseases; neurodevelopmental disorders; molecular biology; big data mining
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Recent Research on Dry Eye
edited by Liat Gantz
submission deadline 30 Sep 2025 | 3 articles | Viewed by 3352 | Submission Open
Keywords: dry eye; meibomian gland dysfunction; ocular surface disease
(This special issue belongs to the Section Molecular and Translational Medicine)
Recent Advances in Obesity-Related Metabolic Diseases: 2nd Edition
edited by Sandip Mukherjee
submission deadline 30 Sep 2025 | 2 articles | Viewed by 3328 | Submission Open
Keywords: obesity; metabolism; adipose tissue; liver inflammation; hyperglycemia; hyperlipidemia; cardiovascular diseases; new drug targets; translational studies
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Exploring Protein-Ligand Interaction: Key Insights for Drug Discovery submission deadline 30 Sep 2025 | 2 articles | Viewed by 3246 | Submission Open
Keywords: protein; ligand; bio(macro)molecule; drug; interaction; binding; spectroscopy; calorimetry; molecular docking; molecular dynamics simulation
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Next-Generation Nanoparticles: Innovations in Biomedical Applications and Theranostics
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 3128 | Submission Open
Keywords: nanoparticles; nanoconjugates; antimicrobial agents; anticancer agents; biomedical applications
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Immunometabolic Determinants of Gut–Liver Axis Health submission deadline 30 Sep 2025 | 1 articles | Viewed by 2973 | Submission Open
Keywords: gut microbiota; 'entero-hepatic' axis; gut– liver axis; immunometabolism
(This special issue belongs to the Section Immunology and Immunotherapy)
Molecular Regulation of Spermatozoa—Second Edition
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 2972 | Submission Open
Keywords: spermatogenesis; spermiogenesis; sperm; capacitation; acrosome reaction; hyperactivation; fertilization; male infertility; antioxidants; redox regulation
(This special issue belongs to the Section Cell Biology and Pathology)
Advanced Cancer Diagnosis and Treatment: Third Edition
edited by and Hideshi Ishii
submission deadline 30 Sep 2025 | 3 articles | Viewed by 2969 | Submission Open
Keywords: cancer biology; epigenetics; early detection; diagnosis; biodiagnosis; novel therapeutics; new paradigms
(This special issue belongs to the Section Cancer Biology and Oncology)
Mechanomedicine: Exploring Mechanobiology at the Intersection of Engineering and Biology
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 2132 | Submission Open
Keywords: mechanomedicine; mechanobiology; microphysiological systems; bioengineering; forces
(This special issue belongs to the Section Biomedical Engineering and Materials)
Impacts of Exercise, Nutrition, Obesity, Metabolism and Ageing on Regenerative Medicine and Their Applications in Tissue Engineering and Therapeutics
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 1675 | Submission Open
Keywords: obesity; exercise; nutrition (diet); obesity; metabolism; ageing; regenerative medicine; tissue engineering; therapeutics
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Vascular Pathologies in the Omics Era
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1631 | Submission Open
Keywords: vascular pathology; blood vessels; omics era; epigenetics; genomics; transcriptomics; proteomics; metabolomics
(This special issue belongs to the Section Cell Biology and Pathology)
Inherited Retinal Diseases: From Pathomolecular Mechanisms to Therapeutic Strategies, 2nd Edition submission deadline 30 Sep 2025 | 1 articles | Viewed by 1390 | Submission Open
Keywords: blindness; gene and protein function; pathogenesis; personalized diagnosis; precision therapy; retina; retinal degeneration
(This special issue belongs to the Section Molecular and Translational Medicine)
Biomedical Devices—Applications for Disease Treatment and Tissue Regeneration
edited by Eleni Papachristou
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1310 | Submission Open
Keywords: biomedical devices; mesenchymal stem cell; biomedical applications; Tissue engineering
(This special issue belongs to the Section Biomedical Engineering and Materials)
Oral Cancer: From Pathophysiology to Novel Therapeutic Approach
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1295 | Submission Open
Keywords: oral cancer and pathophysiology; molecular mechanisms; biomarkers; immunological and targeted therapy; precision medicine and personalized therapies
(This special issue belongs to the Section Molecular and Translational Medicine)
Advanced Research in Metabolic Syndrome (2nd Edition)
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1133 | Submission Open
Keywords: obesity; diabetes; dyslipidemia; hypertension; microcirculatory damage; ischemia– reperfusion; necro-apopto-autophagy; laboratory animals; bioactive agents
(This special issue belongs to the Section Cell Biology and Pathology)
Hearing Loss: Mechanisms and Targeted Interventions
edited by Pavlidis Pavlos
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1093 | Submission Open
Keywords: hearing loss; syndromes; anatomy and physiology of the ear; implants; cochlear implantation; diseases of the middle ear; rehabilitation
(This special issue belongs to the Section Cell Biology and Pathology)
New Advances in Ovarian Cancer
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 989 | Submission Open
Keywords: ovarian cancer; biomarkers; cell biology; gene regulation; target therapy; therapeutic resistance; precision medicine
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Immunotherapy and Radiation Therapy for Cancer (2nd Edition)
edited by and Benjamin Spieler
submission deadline 30 Sep 2025 | 1 articles | Viewed by 984 | Submission Open
Keywords: radiotherapy; immunotherapy; outcome; toxicity; normal tissue; abscopal; tumor; systemic; local; response
(This special issue belongs to the Section Cancer Biology and Oncology)
Molecular and Cellular Research in Diabetes and Metabolic Diseases
edited by Miwon Ahn
submission deadline 30 Sep 2025 | 1 articles | Viewed by 983 | Submission Open
Keywords: insulin exocytosis; pre-diabetes; type 2 diabetes; organ cross-talk; diabetes drugs; diabetes clinical study; glucose homeostasis
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Advanced Molecular Mechanisms and Treatment of Neurological Diseases
edited by and Yanbo Yang
submission deadline 30 Sep 2025 | 1 articles | Viewed by 959 | Submission Open
Keywords: neurological disease; molecular mechanisms; neuroinflammation; metabolism; biomarkers; neuroprotection; gene therapy; omics; drug discovery; personalized medicine
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Epigenetic Regulation of Kidney Development
edited by Hongbing Liu
submission deadline 30 Sep 2025 | 1 articles | Viewed by 942 | Submission Open
Keywords: epigenetic regulation; kidney development; gene expression patterns; targeted therapeutic strategies; epigenetic regulation of kidney development
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Epilepsy: Pathomechanism, Diagnostics, and Novel Treatment Options submission deadline 30 Sep 2025 | 1 articles | Viewed by 698 | Submission Open
Keywords: epilepsy; pathophysiology; neurobiology; molecular pathways; experimental models of epilepsy; neuroinflammation; seizure prediction; biomarker discovery; electrophysiological studies; precision neurology
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Integrative and Preventive Biomarkers for Cardiometabolic Diseases
edited by Tandi E. Matsha and
submission deadline 30 Sep 2025 | Viewed by 698 | Submission Open
Keywords: metabolic health; diabetes; cardiovascular disease; obesity; biomarkers; inflammation; endocrine; integrative medicine; epigenetics
(This special issue belongs to the Section Molecular and Translational Medicine)
Pathogenesis and Targeted Therapy of Autoimmune Diseases
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 662 | Submission Open
Keywords: autoimmune diseases; pathogenesis; targeted therapy
(This special issue belongs to the Section Molecular and Translational Medicine)
Medical Imaging in Brain Tumor: Charting the Future submission deadline 30 Sep 2025 | Viewed by 627 | Submission Open
Keywords: brain tumor diagnosis; artificial intelligence (AI) in medical imaging; imaging biomarkers for brain tumor; detection; segmentation and classification; radiomics and radiogenomics; precision oncology; deep learning and machine learning; neuro oncology; digital pathology; treatment response monitoring
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Innovations and Prospects in Single Cell RNA-seq for Biomedical Research
edited by
submission deadline 30 Sep 2025 | Viewed by 432 | Submission Open
Keywords: bioinformatics; cellular heterogeneity; methodology; molecular biology; single-cell RNA sequencing; single-nucleus RNA sequencing; tissue heterogeneity; transcriptomics
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
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