Next Article in Journal
Optimal and Quasi-Optimal Automatic Tuning of Vibration Neutralizers
Next Article in Special Issue
Analytical Study of Nonlinear Flexural Vibration of a Beam with Geometric, Material and Combined Nonlinearities
Previous Article in Journal
Railway Bridge Runability Safety Analysis in a Vessel Collision Event
Previous Article in Special Issue
Energy-Preserving/Group-Preserving Schemes for Depicting Nonlinear Vibrations of Multi-Coupled Duffing Oscillators
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Vibration
Volume 7
Issue 2
10.3390/vibration7020017
Review Report
vibration-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
Article
Peer-Review Record

Antihistamine Medication Blunts Localized-Vibration-Induced Increases in Popliteal Blood Flow

Vibration 2024, 7(2), 351-361; https://doi.org/10.3390/vibration7020017
by Devin Needs 1, Jonathan Blotter 1, Gilbert W. Fellingham 2, Glenn Cruse 3, Jayson R. Gifford 4, Aaron Wayne Johnson 4 and Jeffrey Brent Feland 4,*
Reviewer 1:
Peter Tiidus
Reviewer 2: Anonymous
Vibration 2024, 7(2), 351-361; https://doi.org/10.3390/vibration7020017
Submission received: 26 February 2024 / Revised: 11 March 2024 / Accepted: 27 March 2024 / Published: 29 March 2024
(This article belongs to the Special Issue Feature Papers in Vibration)

Round 1

Reviewer 1 Report

Comments and Suggestions for Authors

This is an overall interesting study which provides evidence for potential histamine related regulation of local blood flow resulting from mechanical vibratory massage.

Two points the authors should also address:

1. The lack of randomization of the order of treatment, while noted was not fully justified in the manuscript. Eg. why could the treatments not be separated out by say a week instead of 24 hours. The current protocol cannot fully rule out an order effect. Further justification/comment on this is necessary as is the acknowledgement of the possible influence of the order effect on the results.

2. While there is in these findings a modest effect of the vibratory intervention on arterial blood flow (as has also been demonstrated previously), a statistically significant effect is not necessarily a physiologically significant effect. What if any effect/benefit might be derived from the modest increases in bloodflow seen in this and other similar studies. This may just be an intellectually interesting finding without any real physiological or therapeutic benefits. This possibility should also be acknowledged.

Author Response

Please see the attachment

Author Response File: Author Response.docx

Reviewer 2 Report

Comments and Suggestions for Authors

This study focuses on the release of histamine to discuss the mechanism by which localized vibration increases blood flow. I generally agree with the authors' insistence in this paper. I have some comments on the notation for the authors.

 

1. Materials and Methods

How about breaking it up into some sections for readability?

 

2. L206-207

This sentence corresponds to a discussion rather than a result.

 

3. L215-216

This sentence corresponds to a discussion rather than a result.

 

4. L263-289

Is it correct to express this phenomenon using these formulas? If the frequency is low, the force will constantly change over time. Conversely, if the frequency is high, I think force is expressed using a formula similar to sound pressure. Also, the amplitude (the distance written in this paper) changes depending on the frequency due to resonance etc. due to the vibration characteristics of the gun head. Please provide a physically accurate description, citing references.

Author Response

Please see the attachment

Author Response File: Author Response.docx

Back to TopTop