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Open AccessCommunication
J. Manuf. Mater. Process. 2017, 1(1), 8; doi:10.3390/jmmp1010008

In Vitro Corrosion and Biological Assessment of Bioabsorbable WE43 Mg Alloy Specimens

1
School of Mechanical and Manufacturing Engineering, Dublin City University, Dublin 9, Ireland
2
Centre for Research in Engineering and Surface Technology, FOCAS Institute, Dublin Institute of Technology, Kevin Street, Dublin 8, Ireland
3
Trinity Centre for Bioengineering, Trinity Biomedical Sciences Institute, and Department of Mechanical and Manufacturing Engineering, School of Engineering, Trinity College Dublin, the University of Dublin, Dublin 2, Ireland
*
Author to whom correspondence should be addressed.
Received: 28 July 2017 / Revised: 28 August 2017 / Accepted: 29 August 2017 / Published: 5 September 2017
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Abstract

Bioabsorbable magnesium (Mg) alloys have several advantages in biomedical implant applications as they reduce certain risks associated with conventional permanent implants. However, limited information is available for WE43 Mg alloy specimens with comparable size to that of biomedical implants such as cardiovascular stents and orthopaedic wires. The present work examines the corrosion and biological properties of WE43 stent precursor tubes and wire specimens suited for orthopaedic implants. The corrosion-induced loss of mechanical integrity as well as the corrosion-induced changes in surface morphology of the specimens are elucidated and compared. Cell viability assays were performed with human umbilical vein endothelial cells (HUVECs). It was observed that Mg ions released from the WE43 alloy acted as a growth stimulator of HUVECs. View Full-Text
Keywords: bioabsorbable; biocompatible; magnesium bioabsorbable; biocompatible; magnesium
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Galvin, E.; Jaiswal, S.; Lally, C.; MacDonald, B.; Duffy, B. In Vitro Corrosion and Biological Assessment of Bioabsorbable WE43 Mg Alloy Specimens. J. Manuf. Mater. Process. 2017, 1, 8.

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