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Proceedings 2017, 1(4), 532; doi:10.3390/proceedings1040532

Comparison of ITO and IrOx-Modified ITO Interdigitated Electrodes for Electrical Cell-Substrate Impedance Sensing (ECIS) Applications

Institut des Nanotechnologies de Lyon UMR 5270 CNRS, Université Claude Bernard Lyon 1, INSA, Villeurbanne, France
Presented at the Eurosensors 2017 Conference, Paris, France, 3–6 September 2017.
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Published: 9 August 2017
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Abstract

This study compares the sensitivity of interdigitated electrodes (IDEs) used in Electrical Cell-Substrate Impedance Sensing (ECIS). IDEs made of indium tin oxide (ITO) and ITO coated with iridium oxide (IrOx) were used for ECIS measurements with the human breast cancer cell line, MCF-7. The results indicate that IrOx-modified ITO electrodes provide both biocompatibility and higher cell sensitivity compared to ITO electrodes. We also found that the quantity of IrOx required to generate such a sensitivity improvement is sufficiently low to not interfere with the visualization of the cells under study. IrOx-modified ITO electrodes are therefore promising sensors for ECIS applications.
Keywords: ECIS; electrode sensitivity; bioimpedance measurements; ITO; IrOx coating; MCF-7 ECIS; electrode sensitivity; bioimpedance measurements; ITO; IrOx coating; MCF-7
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Martinez, J.; Montalibet, A.; McAdams, E.; Faivre, M.; Ferrigno, R. Comparison of ITO and IrOx-Modified ITO Interdigitated Electrodes for Electrical Cell-Substrate Impedance Sensing (ECIS) Applications. Proceedings 2017, 1, 532.

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