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Proceedings 2017, 1(4), 313; doi:10.3390/proceedings1040313

Particle Separation with Deterministic Lateral Displacement (DLD): The Anisotropy Effect

1
CEA, LETI, MINATEC Campus, F-38054 Grenoble, France
2
Université Grenoble Alpes, F-38000 Grenoble, France
Presented at the Eurosensors 2017 Conference, Paris, France, 3–6 September 2017.
*
Author to whom correspondence should be addressed.
Published: 18 August 2017
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Abstract

Deterministic lateral displacement (DLD) is a passive and label-free microfluidic separation technique with a strong potential for biological sample preparation purposes. Numerical and experimental models have been proposed so far to predict the particle behavior in DLD channels. However, they do not take into account the influence of the pillar anisotropy that induces a secondary pressure gradient in the direction perpendicular to the main flow. The influence of the pillar geometry on the anisotropy magnitude is presented. We show that anisotropy impacts the trajectory of particles in DLD devices and should be included in predictive models for the critical diameter.
Keywords: deterministic lateral displacement; micro and nanoparticle separation; anisotropy effect deterministic lateral displacement; micro and nanoparticle separation; anisotropy effect
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Pariset, E.; Berthier, J.; Pudda, C.; Navarro, F.; Icard, B.; Agache, V. Particle Separation with Deterministic Lateral Displacement (DLD): The Anisotropy Effect. Proceedings 2017, 1, 313.

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