Next Article in Journal
Cytotoxic Effects of Alchemilla mollis (Buser) Rothm. Extracts on MCF 7 Cell Line
Previous Article in Journal
The Sandcastle by the Sea. IT and AR for Survey, Graphical Analysis and Representation of the “Skyscraper” by R. Bibbiani in La Spezia
Article Menu

Article Versions

Export Article

Open AccessAbstract
Proceedings 2017, 1(10), 1028; doi:10.3390/proceedings1101028

Antiproliferative Effect of Methanolic Extract of Linum arboreum on A549 Cells

Department of Biology, Science and Art Faculty, Uludag University, Bursa 16059, Turkey
Presented at the 2nd International Conference on Natural Products for Cancer Prevention and Therapy, Kayseri, Turkey, 8–11 November 2017.
*
Author to whom correspondence should be addressed.
Published: 14 November 2017
Download PDF [149 KB, uploaded 14 November 2017]

Abstract

Many anticancer drugs in clinical use are natural product derived from natural sources. Today, investigations of anti cancer effect of different natural products are increase. The aimed of the current study was to investigate possible antiproliferative effects of methanolic extract of Linum arboreum leaves (MELAL) and fruits (MELAF). Linumarboreum is a plant species that member of Linacea efamily. We evaluated the antiproliferative effect of MELAL and MELAF on human lung carcinomacells A549 by XTT assay. Cells exposed different concentration of MELAL and MELAF (0.1–2000 µg/mL) for 24 h. IC50 value was determined 0.771 ± 0.043 µg/mL of MELAL and IC50 value was determined 1.456 ± 0.995 µg/mL of MELAF. MELAL has shown higher antiproliferative activity compare with MELAF. Alsoboth of MELAL and MELAF have higher antiproliferative activity with low IC50 values in compared cisplatin. Especially MELAL has shown strong anticancer activity with low IC50 value. Nevertheless, anti cancer activity of MELAL should be supported by further studies.
Keywords: Linumarboreum; XTT; A549 Linumarboreum; XTT; A549
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Vatan, O.; Yılmaz, O.; Huriyet, H.; Cavas, T.; Cinkılıç, N. Antiproliferative Effect of Methanolic Extract of Linum arboreum on A549 Cells. Proceedings 2017, 1, 1028.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Proceedings EISSN 2504-3900 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top