Biocompatibility of 3D-Printed Methacrylate for Hearing Devices
Abstract
:1. Introduction
2. Materials and Methods
3. Results
Qualitative Gas Chromatography–Mass Spectrometry
4. Discussion
5. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Manufacturing Parameters | Hazardous Ingredient(s) w/w % | Physical Properties |
---|---|---|
Photocured samples were built with Perfactory® DDP 4 M 3D printer. Manufacturing parameters are z-height: 67.98 mm, voxel: 100 µm and light power: 180 Mw/dm2. | 60–80% Proprietary methacrylate oligomers; 15–30% Proprietary methacrylate monomers; 1–2% diphenyl 2,4,6-trimethylbenzoyl. | Flexural strength: 60–80 MPa; Flexural modulus: 1200–1500 MPa; Elongation at break: 2–4%; Tensile strength: 40–48 MPa; Tensile modulus: 2150–3250 MPa; Izod impact: 30 J/m; HDT: 75° at 1.82 MPa; Hardness, D Scale: 82–85; Viscosity: 320 cP at 30 °C. |
24 h | 48 h | 72 h | 96 h | |
---|---|---|---|---|
Lethal endpoints | ||||
Coagulation | . | . | . | . |
Lack of somite formation | . | . | . | . |
Non-detachment of tail-bud | . | . | . | . |
Lack of heart-beat | . | . | . | . |
Sublethal developmental endpoints | ||||
Development of eyes | . | . | . | . |
Spontaneous movement | . | . | . | . |
Hypopigmentation | . | . | . | |
Formation of edemata | . | . | . | |
Endpoints of teratogenicity | ||||
Spinal curvature and malformation of tail | . | . | . | . |
Yolk deformation | . | . | . | . |
Growth retardation | . |
Non-Treated E-Shell 450 Methacrylate | Ethanol-Treated E-Shell 450 Methacrylate |
---|---|
2-Hydroxyethyl methacrylate | Propylene glycol methyl ether |
Propylene glycol methyl ether | m-Xylene |
Octyl Acrylate | Methyl 3-methoxy-2-methylpropanoate |
2-Propyl-1-pentanol | Toluene |
Benzaldehyde | Undecane |
Tetrahydrofufuryl Butyrate | |
Cyclohexanone | |
Cyclomethicone 5 | |
Cyclomethicone 6 | |
2,6,11-Trimethyldodecane | |
Ethylbenzene | |
N-[1-(4-Hydroxy-5-hydroxymethyltetrahydrofuran-2-yl)-4-oxo-1,4-dihydropyrimidin-2-yl]benzamide | |
Texanol | |
Methyl 3-methoxy-2-methylpropanoate | |
Toluene | |
Undecane |
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Alifui-Segbaya, F.; George, R. Biocompatibility of 3D-Printed Methacrylate for Hearing Devices. Inventions 2018, 3, 52. https://doi.org/10.3390/inventions3030052
Alifui-Segbaya F, George R. Biocompatibility of 3D-Printed Methacrylate for Hearing Devices. Inventions. 2018; 3(3):52. https://doi.org/10.3390/inventions3030052
Chicago/Turabian StyleAlifui-Segbaya, Frank, and Roy George. 2018. "Biocompatibility of 3D-Printed Methacrylate for Hearing Devices" Inventions 3, no. 3: 52. https://doi.org/10.3390/inventions3030052