Feature Importance for Human Epithelial (HEp-2) Cell Image Classification†
AbstractIndirect Immuno-Fluorescence (IIF) microscopy imaging of human epithelial (HEp-2) cells is a popular method for diagnosing autoimmune diseases. Considering large data volumes, computer-aided diagnosis (CAD) systems, based on image-based classification, can help in terms of time, effort, and reliability of diagnosis. Such approaches are based on extracting some representative features from the images. This work explores the selection of the most distinctive features for HEp-2 cell images using various feature selection (FS) methods. Considering that there is no single universally optimal feature selection technique, we also propose hybridization of one class of FS methods (filter methods). Furthermore, the notion of variable importance for ranking features, provided by another type of approaches (embedded methods such as Random forest, Random uniform forest) is exploited to select a good subset of features from a large set, such that addition of new features does not increase classification accuracy. In this work, we have also, with great consideration, designed class-specific features to capture morphological visual traits of the cell patterns. We perform various experiments and discussions to demonstrate the effectiveness of FS methods along with proposed and a standard feature set. We achieve state-of-the-art performance even with small number of features, obtained after the feature selection. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Gupta, V.; Bhavsar, A. Feature Importance for Human Epithelial (HEp-2) Cell Image Classification. J. Imaging 2018, 4, 46.
Gupta V, Bhavsar A. Feature Importance for Human Epithelial (HEp-2) Cell Image Classification. Journal of Imaging. 2018; 4(3):46.Chicago/Turabian Style
Gupta, Vibha; Bhavsar, Arnav. 2018. "Feature Importance for Human Epithelial (HEp-2) Cell Image Classification." J. Imaging 4, no. 3: 46.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.