The Role of Long Non-Coding RNAs in Osteosarcoma
AbstractLong non-coding RNAs (lncRNAs) constitute non-protein coding transcripts with a size > than 200 nucleotides. They are involved in many cellular processes, such as chromatin remodelling, transcription, and gene expression. They play a role in the development, progression, and invasion of many human cancers, including osteosarcoma. This rare tumor entity predominantly arises in children and young adults. Treatment consists of polychemotherapy and surgical resection, increasing survival rates up to 60%. In the present review, the role of lncRNAs with prognostic, predictive, therapeutic, and diagnostic significance in osteosarcoma is discussed. Moreover, their potential application in clinical practice is highlighted. View Full-Text
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Smolle, M.A.; Pichler, M. The Role of Long Non-Coding RNAs in Osteosarcoma. Non-Coding RNA 2018, 4, 7.
Smolle MA, Pichler M. The Role of Long Non-Coding RNAs in Osteosarcoma. Non-Coding RNA. 2018; 4(1):7.Chicago/Turabian Style
Smolle, Maria A.; Pichler, Martin. 2018. "The Role of Long Non-Coding RNAs in Osteosarcoma." Non-Coding RNA 4, no. 1: 7.
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