Virulence Factors as Targets for Anticryptococcal Therapy
AbstractThe global mortality due to cryptococcosis caused by Cryptococcus neoformans or C. gattii is unacceptably high. Currently available therapies are decades old and may be impacted by drug resistance. Therefore, the need for more effective antifungal drugs for cryptococcosis is evident. A number of Cryptococcus virulence factors have been studied in detail, providing crucial information about the fungal biology and putative molecular targets for antifungals. This review focuses on the use of well-described virulence factors of Cryptococcus as potential anticryptococcal agents. View Full-Text
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Azevedo, R.V.D.M.; Rizzo, J.; Rodrigues, M.L. Virulence Factors as Targets for Anticryptococcal Therapy. J. Fungi 2016, 2, 29.
Azevedo RVDM, Rizzo J, Rodrigues ML. Virulence Factors as Targets for Anticryptococcal Therapy. Journal of Fungi. 2016; 2(4):29.Chicago/Turabian Style
Azevedo, Renata V.D.M.; Rizzo, Juliana; Rodrigues, Marcio L. 2016. "Virulence Factors as Targets for Anticryptococcal Therapy." J. Fungi 2, no. 4: 29.
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