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Sinusitis 2017, 2(3), 5; doi:10.3390/sinusitis2030005

Multimodal Frequency Treatment for Facial Pain Caused by Chronic Rhinosinusitis: A Pilot Study

1
Sarah Bush Lincoln Health Center, 1000 Health Center Dr., Mattoon, IL 61938, USA
2
Department of Pain Management, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
3
Bonutti Technologies, 2600 S Raney St., Effingham, IL 62401, USA
4
AxioSonic, 2600 S Raney St., Effingham, IL 62401, USA
*
Author to whom correspondence should be addressed.
Received: 1 August 2017 / Revised: 24 August 2017 / Accepted: 29 August 2017 / Published: 4 September 2017
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Abstract

Chronic rhinosinusitis (CRS) is a common disease that affects over 200 million patients worldwide. CRS often presents with facial pain, which is considered an important criterion for the diagnosis of CRS. A single-arm clinical study was designed to test the effect of simultaneous high (1 MHz) and low frequencies (70–80 Hz) on facial pain in 14 CRS patients at the Sarah Bush Lincoln Health Center, Mattoon, IL, USA. We used two quality of life (QOL) instruments to test the effect of multimodal frequencies on patients suffering from CRS: the Brief Pain Inventory Short Form (BPI-SF), and the Sino-Nasal Outcome Test (SNOT-22). Mean BPI-SF severity scores improved by 0.80 points (Wilcoxon rank sum test p < 0.01) in all 14 patients. In patients with baseline facial pain (n = 9), the scores improved by an average of 1.5 (p < 0.01) points in the pain severity domain and by 1.4 points in the pain interference domain. Additionally, the mean improvement in SNOT-22 scores was 14.11 (p < 0.05), which is above the minimal clinically-important difference (MCID) of nine points. Our pilot study indicates that multimodal vibration frequencies applied over the facial sinuses reduce pain, possibly through the reduction of the inflammatory response and modulation of the pain receptors. This study suggests the possibility that combining different frequencies could have an enhanced effect on reducing CRS-related facial pain. View Full-Text
Keywords: maxillary sinus; frontal sinus; chronic rhinosinusitis; facial pain; mechanical vibration; nociceptive modulation maxillary sinus; frontal sinus; chronic rhinosinusitis; facial pain; mechanical vibration; nociceptive modulation
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Smith, M.; Berenger, P.G.; Bonutti, P.; Ramakrishnan, A.P.; Beyers, J.; Ramakrishnan, V. Multimodal Frequency Treatment for Facial Pain Caused by Chronic Rhinosinusitis: A Pilot Study. Sinusitis 2017, 2, 5.

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