Next Article in Journal / Special Issue
“Sacred Work”: Reflections on the Professional and Personal Impact of an Interdisciplinary Palliative Oncology Clinical Experience by Social Work Learners
Previous Article in Journal
Risk Factor Assessment of Hospice Patients Readmitted within 7 Days of Acute Care Hospital Discharge
Previous Article in Special Issue
Cancer-Related Information Seeking and Scanning Behaviors among Older Chinese Adults: Examining the Roles of Fatalistic Beliefs and Fear
Article Menu

Export Article

Open AccessArticle
Geriatrics 2018, 3(1), 5; https://doi.org/10.3390/geriatrics3010005

Factors Influencing Global Health Related Quality of Life in Elderly Cancer Patients: Results of a Secondary Data Analysis

1
Institute of Health and Nursing Sciences, Medical Faculty, Martin Luther University Halle-Wittenberg, Magdeburger Str. 8, 06112 Halle (Saale), Germany
2
Department of Radiation Oncology, University Hospital Halle (Saale), Medical Faculty, Martin Luther University Halle-Wittenberg, Ernst-Grube-Str. 40 06120 Halle (Saale), Germany
3
Health Sciences, University of Southampton, SO17 1BJ Southampton, UK
4
Institute for Medical Epidemiology, Biostatistics, and Informatics, Medical Faculty, Martin Luther University Halle-Wittenberg, Magdeburger Str. 8, 06112 Halle (Saale), Germany
5
Cancer Sciences, University of Southampton, SO17 1BJ Southampton, UK
*
Author to whom correspondence should be addressed.
Received: 14 November 2017 / Revised: 23 January 2018 / Accepted: 24 January 2018 / Published: 30 January 2018
(This article belongs to the Special Issue Oncology Care and Research in the Elderly)
View Full-Text   |   Download PDF [220 KB, uploaded 30 January 2018]   |  

Abstract

Cancer treatment for elderly patients is often complicated by poor physical condition, impaired functioning and comorbidities. Patient reported health related quality of life (HRQOL) can contribute to decisions about treatment goals and supportive therapy. Knowledge about factors influencing HRQOL is therefore needed for the development of supportive measures and care pathways. An exploratory secondary data analysis on 518 assessments of the European Organisation for Research and Treatment of Cancer (EORTC) core questionnaire (EORTC QLQ-C30) and the elderly module (EORTC QLQ-ELD14) was performed to identify factors predictive for global HRQOL. Preliminary simple and multivariable regression analyses were conducted resulting in a final model comprising sociodemographic and disease specific variables and scales of the QLQ-C30 and QLQ-ELD14. Age, sex and disease related variables explained only part of the variance of global HRQOL (adjusted R2 = 0.203). In the final model (adjusted R2 = 0.504) fatigue, social function, burden of illness and joint stiffness showed possible influence on global HRQOL. Fatigue, social function and burden of illness seem to have the largest impact on global HRQOL of elderly cancer patients. Further prospective studies should examine these domains. Actionable symptoms should be given special attention to initiate targeted supportive measures aiming to maximize HRQOL of older cancer patients. View Full-Text
Keywords: geriatric oncology; health related quality of life; social function; fatigue; burden of illness; supportive care geriatric oncology; health related quality of life; social function; fatigue; burden of illness; supportive care
Figures

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Schmidt, H.; Nordhausen, T.; Boese, S.; Vordermark, D.; Wheelwright, S.; Wienke, A.; Johnson, C.D. Factors Influencing Global Health Related Quality of Life in Elderly Cancer Patients: Results of a Secondary Data Analysis. Geriatrics 2018, 3, 5.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Geriatrics EISSN 2308-3417 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top