Next Article in Journal
Microtechnology-Based Multi-Organ Models
Previous Article in Journal
Comparative N-Glycosylation Analysis of the Fc Portions of a Chimeric Human Coagulation Factor VIII and Immunoglobulin G1
Article Menu

Export Article

Open AccessArticle
Bioengineering 2017, 4(2), 45; doi:10.3390/bioengineering4020045

OpenDrop: An Integrated Do-It-Yourself Platform for Personal Use of Biochips

Gaudi Labs, Lucern 6003, Switzerland
*
Author to whom correspondence should be addressed.
Academic Editor: Hyun Jung Kim
Received: 1 April 2017 / Revised: 6 May 2017 / Accepted: 11 May 2017 / Published: 19 May 2017
View Full-Text   |   Download PDF [7352 KB, uploaded 19 May 2017]   |  

Abstract

Biochips, or digital labs-on-chip, are developed with the purpose of being used by laboratory technicians or biologists in laboratories or clinics. In this article, we expand this vision with the goal of enabling everyone, regardless of their expertise, to use biochips for their own personal purposes. We developed OpenDrop, an integrated electromicrofluidic platform that allows users to develop and program their own bio-applications. We address the main challenges that users may encounter: accessibility, bio-protocol design and interaction with microfluidics. OpenDrop consists of a do-it-yourself biochip, an automated software tool with visual interface and a detailed technique for at-home operations of microfluidics. We report on two years of use of OpenDrop, released as an open-source platform. Our platform attracted a highly diverse user base with participants originating from maker communities, academia and industry. Our findings show that 47% of attempts to replicate OpenDrop were successful, the main challenge remaining the assembly of the device. In terms of usability, the users managed to operate their platforms at home and are working on designing their own bio-applications. Our work provides a step towards a future in which everyone will be able to create microfluidic devices for their personal applications, thereby democratizing parts of health care. View Full-Text
Keywords: droplet microfluidics; lab-on-a chip; electromicrofluidics; design automation; open source hardware; do-it-yourself biology droplet microfluidics; lab-on-a chip; electromicrofluidics; design automation; open source hardware; do-it-yourself biology
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Alistar, M.; Gaudenz, U. OpenDrop: An Integrated Do-It-Yourself Platform for Personal Use of Biochips. Bioengineering 2017, 4, 45.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Bioengineering EISSN 2306-5354 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top