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Inorganics 2017, 5(1), 4; doi:10.3390/inorganics5010004

Anticancer Applications and Recent Investigations of Metallodrugs Based on Gallium, Tin and Titanium

1
Departamento de Biología y Geología, Física y Química Inorgánica, Universidad Rey Juan Carlos, Calle Tulipán, s/n, E-28933 Móstoles (Madrid), Spain
2
Faculté des Sciences, Département de Chimie, Université Abdelmalek Essâadi, 93030 Tétouan, Morocco
*
Author to whom correspondence should be addressed.
Academic Editor: Luigi Messori
Received: 5 December 2016 / Revised: 4 January 2017 / Accepted: 5 January 2017 / Published: 12 January 2017
(This article belongs to the Special Issue Tumor Inhibiting Metal Complexes)

Abstract

For more than 100 years metal complexes have been extensively used in therapy and since the discovery of cisplatin the research in this field has expanded exponentially. The scientific community is always in search of new alternatives to platinum compounds and a wide variety of metallodrugs based on other metals have been reported with excellent therapeutic results. This short review focuses on the work that our research group has carried out since 2007 in collaboration with others and centers on the preparation of organogallium(III) compounds, organotin(IV) derivatives, and titanocene(IV) complexes together with the study of their cytotoxic anticancer properties. View Full-Text
Keywords: metallodrugs; cisplatin; gallium; tin; titanium; cancer; nanostructures metallodrugs; cisplatin; gallium; tin; titanium; cancer; nanostructures
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Ellahioui, Y.; Prashar, S.; Gómez-Ruiz, S. Anticancer Applications and Recent Investigations of Metallodrugs Based on Gallium, Tin and Titanium. Inorganics 2017, 5, 4.

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