Photonics 2014, 1(1), 9-32; doi:10.3390/photonics1010009
Review

Instrumentation in Diffuse Optical Imaging

Received: 15 December 2013; in revised form: 6 January 2014 / Accepted: 7 January 2014 / Published: 20 March 2014
(This article belongs to the Special Issue Biomedical Optics and Optical Imaging)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Diffuse optical imaging is highly versatile and has a very broad range of applications in biology and medicine. It covers diffuse optical tomography, fluorescence diffuse optical tomography, bioluminescence and a number of other new imaging methods. These methods of diffuse optical imaging have diversified instrument configurations, but share the same core physical principle: light propagation in highly diffusive media, i.e., biological tissue. In this review, the author summarizes the latest development in instrumentation and methodology available to diffuse optical imaging in terms of system architecture, light source, photo-detection, spectral separation, signal modulation and, lastly, imaging contrast.
Keywords: diffuse optical imaging; instrumentation; fluorescence; molecular imaging; bioluminescence; tomography; clinical; preclinical
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MDPI and ACS Style

Zhang, X. Instrumentation in Diffuse Optical Imaging. Photonics 2014, 1, 9-32.

AMA Style

Zhang X. Instrumentation in Diffuse Optical Imaging. Photonics. 2014; 1(1):9-32.

Chicago/Turabian Style

Zhang, Xiaofeng. 2014. "Instrumentation in Diffuse Optical Imaging." Photonics 1, no. 1: 9-32.

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