Informatics 2014, 1(1), 72-99; doi:10.3390/informatics1010072
Review

Molecular Imaging of Bacterial Infections in vivo: The Discrimination between Infection and Inflammation

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Received: 18 March 2014; in revised form: 6 May 2014 / Accepted: 13 May 2014 / Published: 30 May 2014
(This article belongs to the Special Issue Biomedical Imaging and Visualization)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Molecular imaging by definition is the visualization of molecular and cellular processes within a given system. The modalities and reagents described here represent a diverse array spanning both pre-clinical and clinical applications. Innovations in probe design and technologies would greatly benefit therapeutic outcomes by enhancing diagnostic accuracy and assessment of acute therapy. Opportunistic pathogens continue to pose a worldwide threat, despite advancements in treatment strategies, which highlights the continued need for improved diagnostics. In this review, we present a summary of the current clinical protocol for the imaging of a suspected infection, methods currently in development to optimize this imaging process, and finally, insight into endocarditis as a model of infectious disease in immediate need of improved diagnostic methods.
Keywords: molecular imaging; endocarditis; infection; inflammation; Staphylococcus aureus
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MDPI and ACS Style

Eggleston, H.; Panizzi, P. Molecular Imaging of Bacterial Infections in vivo: The Discrimination between Infection and Inflammation. Informatics 2014, 1, 72-99.

AMA Style

Eggleston H, Panizzi P. Molecular Imaging of Bacterial Infections in vivo: The Discrimination between Infection and Inflammation. Informatics. 2014; 1(1):72-99.

Chicago/Turabian Style

Eggleston, Heather; Panizzi, Peter. 2014. "Molecular Imaging of Bacterial Infections in vivo: The Discrimination between Infection and Inflammation." Informatics 1, no. 1: 72-99.

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