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Open AccessCase Report
Children 2017, 4(12), 113; doi:10.3390/children4120113

A Rare Case of Pure Erythroid Sarcoma in a Pediatric Patient: Case Report and Literature Review

1
Department of Hematology, Hospital General Universitario de Alicante, 03010 Alicante, Spain
2
Department of Anatomic Pathology, Hospital General Universitario de Alicante, 03010 Alicante, Spain
3
Department of Pediatrics, Hospital General Universitario de Alicante, 03010 Alicante, Spain
4
Department of Hematology, Hospital Universitario La Fe de Valencia, 46009 Valencia, Spain
5
Department of Hematology, Hospital de Elda, 03600 Elda, Alicante, Spain
*
Author to whom correspondence should be addressed.
Received: 4 November 2017 / Revised: 16 December 2017 / Accepted: 19 December 2017 / Published: 20 December 2017
(This article belongs to the Section Oncology & Hematology)
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Abstract

We describe an exceptional case of erythroid sarcoma in a pediatric patient as a growing orbital mass with no evidence of morphologic bone marrow involvement, who was finally diagnosed of pure erythroid sarcoma based on histopathology and flow cytometry criteria. We discuss the contribution of standardized eight-color flow cytometry as a rapid and reliable diagnostic method. The use of normal bone marrow databases allowed us to identify small aberrant populations in bone marrow and later confirm the diagnosis in the neoplastic tissue. View Full-Text
Keywords: red blood cell disorders; leukemias; acute; hematology; immunophenotype; sarcomas; including soft tissue; non-rhabdoid red blood cell disorders; leukemias; acute; hematology; immunophenotype; sarcomas; including soft tissue; non-rhabdoid
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Manresa, P.; Tarín, F.; Niveiro, M.; Tasso, M.; Alda, O.; López, F.; Sarmiento, H.; Verdú, J.J.; De Paz, F.; López, S.; Del Cañizo, M.; Such, E.; Barragán, E.; Martirena, F. A Rare Case of Pure Erythroid Sarcoma in a Pediatric Patient: Case Report and Literature Review. Children 2017, 4, 113.

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