Breast Cancer Stem Cells
AbstractBreast cancer stem cells (BCSC) have been implicated in tumor initiation, progression, metastasis, recurrence, and resistance to therapy. The origins of BCSCs remain controversial due to tumor heterogeneity and the presence of such small side populations for study, but nonetheless, cell surface markers and their correlation with BCSC functionality continue to be identified. BCSCs are driven by persistent activation of developmental pathways, such as Notch, Wnt, Hippo, and Hedgehog and new treatment strategies that are aimed at these pathways are in preclinical and clinical development. View Full-Text
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Crabtree, J.S.; Miele, L. Breast Cancer Stem Cells. Biomedicines 2018, 6, 77.
Crabtree JS, Miele L. Breast Cancer Stem Cells. Biomedicines. 2018; 6(3):77.Chicago/Turabian Style
Crabtree, Judy S.; Miele, Lucio. 2018. "Breast Cancer Stem Cells." Biomedicines 6, no. 3: 77.