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Biomedicines 2016, 4(3), 17; doi:10.3390/biomedicines4030017

In Vitro Anti-Oxidant and Anti-Microbial Potentiality Investigation of Different Fractions of Caryota urens Leaves

1
Department of Pharmacy, International Islamic University Chittagong, Chittagong-4203, Bangladesh
2
Department of Pharmaceutical Sciences, North South University, Dhaka-1229, Bangladesh
3
Department of Pharmacy, University of Science and Technology (USTC), Chittagong-4203, Bangladesh
4
Department of Pharmacy, Northern University Bangladesh, Dhaka-1213, Bangladesh
*
Author to whom correspondence should be addressed.
Academic Editor: Kenneth Cornetta
Received: 29 May 2016 / Revised: 16 July 2016 / Accepted: 19 July 2016 / Published: 27 July 2016
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Abstract

Background: Caryota urens is a member of the Arecaceae family and a common plant in the Southeast Asian region. This plant has been reported as an anti-microbial agent in recent years. Thus, we aimed to find out the MIC (minimum inhibitory concentration) against different pathogenic microorganism. Methods: The leaves of C. urens were extracted and fractioned using different reagents (chloroform, n-hexane and carbon tetrachloride). Disc diffusion method was implemented for the assessment of in vitro anti-microbial potency (500 and 250 µg/disc). Result: The entire fraction showed good effect (with the zone of inhibition 19–25 mm) against both gram positive (Bacillus subtilis, Bacillus megaterium, Bacillus cereus, Sarina lutea) and gram negative (Vibrio mimicus, Shigella boydii, Escherichia coli, Pseudomonas aeruginosa) bacterial pathogens and fungal strains (Aspergillus niger, Saccharomyces cerevisiae). The plants also possess effective free radical scavenging potency with an IC50 of 130.32 µg/mL. Conclusion: This finding reflects a link between the presence of anti-oxidative material and a substantial anti-microbial activity, and substantiates all previous claims against C. urens. View Full-Text
Keywords: anti-microbial; Mueller-Hinton broth; B. cereus; E. coli; anti-oxidant anti-microbial; Mueller-Hinton broth; B. cereus; E. coli; anti-oxidant
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MDPI and ACS Style

Azam, S.; Mahmud, M.K.; Naquib, M.H.; Hossain, S.M.; Alam, M.N.; Uddin, M.J.; Sajid, I.; Hossain, M.S.; Karim, M.S.; Hasan, M.A. In Vitro Anti-Oxidant and Anti-Microbial Potentiality Investigation of Different Fractions of Caryota urens Leaves. Biomedicines 2016, 4, 17.

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