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Biomedicines 2014, 2(1), 50-79; doi:10.3390/biomedicines2010050

Stem Cell Banking for Regenerative and Personalized Medicine

Department of Immunobiology, University of Arizona, PO Box 245221, Tucson, AZ 85724, USA
Received: 19 November 2013 / Revised: 10 January 2014 / Accepted: 17 February 2014 / Published: 26 February 2014
(This article belongs to the Special Issue Feature Papers)
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Abstract

Regenerative medicine, tissue engineering and gene therapy offer the opportunity to treat and cure many of today’s intractable afflictions. These approaches to personalized medicine often utilize stem cells to accomplish these goals. However, stem cells can be negatively affected by donor variables such as age and health status at the time of collection, compromising their efficacy. Stem cell banking offers the opportunity to cryogenically preserve stem cells at their most potent state for later use in these applications. Practical stem cell sources include bone marrow, umbilical cord blood and tissue, and adipose tissue. Each of these sources contains stem cells that can be obtained from most individuals, without too much difficulty and in an economical fashion. This review will discuss the advantages and disadvantages of each stem cell source, factors to be considered when contemplating banking each stem cell source, the methodology required to bank each stem cell source, and finally, current and future clinical uses of each stem cell source.
Keywords: stem cells; banking; cord blood; MSC; cord tissue stem cells; banking; cord blood; MSC; cord tissue
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Harris, D.T. Stem Cell Banking for Regenerative and Personalized Medicine. Biomedicines 2014, 2, 50-79.

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