Vitamin D as an Immunomodulator: Risks with Deficiencies and Benefits of Supplementation
AbstractVitamin D refers to a class of fat-soluble secosteroids often associated with their role in absorption and metabolism of minerals such as calcium and phosphate. In recent years, our understanding of vitamin D has expanded to include its role in modulating the immune system. Of particular focus are the effects of vitamin D deficiency and supplementation on patients suffering from disorders due to dysregulation of the immune system. In patients with multiple sclerosis, rheumatoid arthritis, and inflammatory bowel disease, deficiencies in vitamin D have been associated with an increased risk of disease activity. In this review, we will look at the current state of research in regards to the relationship between vitamin D and immune-dysregulation. We will focus on both the risks associated with vitamin D deficiency as well as the benefits of vitamin D supplementation. View Full-Text
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Goldsmith, J.R. Vitamin D as an Immunomodulator: Risks with Deficiencies and Benefits of Supplementation. Healthcare 2015, 3, 219-232.
Goldsmith JR. Vitamin D as an Immunomodulator: Risks with Deficiencies and Benefits of Supplementation. Healthcare. 2015; 3(2):219-232.Chicago/Turabian Style
Goldsmith, Jason R. 2015. "Vitamin D as an Immunomodulator: Risks with Deficiencies and Benefits of Supplementation." Healthcare 3, no. 2: 219-232.