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Sci. Pharm. 2015, 83(3), 489-500; doi:10.3797/scipharm.1411-08

Metabolite Profiling of Justicia gendarussa Burm. f. Leaves Using UPLC-UHR-QTOF-MS

1
Faculty of Pharmacy, Jember University, Jl. Kalimantan I, 68121, Jember, Indonesia
2
PT. Angler BioChemLab, Plaza Graha Family C-25, 60226, Surabaya, Indonesia
3
Faculty of Pharmacy, Airlangga University, Jl. Dharmawangsa Dalam, 60286, Surabaya, Indonesia
*
Author to whom correspondence should be addressed.
Received: 16 November 2014 / Accepted: 14 April 2015 / Published: 14 April 2015
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Abstract

An ultra-performance liquid chromatography ultra-high-resolution quadrupole-time-of-flight-mass spectrometry (UPLC-UHR-QTOF-MS) metabolite profiling of Justicia gendarussa Burm. f. leaves was performed. PCA and HCA analyses were applied to observe the clustering patterns and inter-sample relationships. It seemed that the concentrations of Ca, P, and Cu in the soil could affect the metabolite profiles of Justicia gendarussa. Six significant metabolites were proposed.
Keywords: Justicia gendarussa; UPLC-UHR-QTOF-MS; PCA; HCA; Sites of cultivation; Significant metabolites Justicia gendarussa; UPLC-UHR-QTOF-MS; PCA; HCA; Sites of cultivation; Significant metabolites
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

NINGSIH, I.Y.; PURWANTI, D.I.; WONGSO, S.; PRAJOGO, B.E.W.; INDRAYANTO, G. Metabolite Profiling of Justicia gendarussa Burm. f. Leaves Using UPLC-UHR-QTOF-MS. Sci. Pharm. 2015, 83, 489-500.

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