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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2015). Articles in this Volume were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Sci. Pharm. 2015, 83(2), 369-376; doi:10.3797/scipharm.1410-14 (registering DOI)

An Efficient, Robust, and Inexpensive Grinding Device for Herbal Samples like Cinchona Bark

1
Analytical Biosciences, Dept. of Pharmacy, Fac. of Health and Med. Sci., Univ. of Copenhagen, Denmark.
2
Natural History Museum of Denmark, University of Copenhagen, Denmark.
*
Author to whom correspondence should be addressed.
Received: 20 October 2014 / Accepted: 19 February 2015 / Published: 19 February 2015
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Abstract

An effective, robust, and inexpensive grinding device for the grinding of herb samples like bark and roots was developed by rebuilding a commercially available coffee grinder. The grinder was constructed to be able to provide various particle sizes, to be easy to clean, and to have a minimum of dead volume. The recovery of the sample when grinding as little as 50 mg of crude Cinchona bark was about 60%. Grinding is performed in seconds with no rise in temperature, and the grinder is easily disassembled to be cleaned. The influence of the particle size of the obtained powders on the recovery of analytes in extracts of Cinchona bark was investigated using HPLC.
Keywords: Grinding; Bark and root; Cinchona bark; HPLC Grinding; Bark and root; Cinchona bark; HPLC
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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HANSEN, S.H.; HOLMFRED, E.; CORNETT, C.; MALDONADO, C.; RØNSTED, N. An Efficient, Robust, and Inexpensive Grinding Device for Herbal Samples like Cinchona Bark . Sci. Pharm. 2015, 83, 369-376.

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