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Sci. Pharm. 2015, 83(2), 353-367; doi:10.3797/scipharm.1410-10

Screening of Panamanian Plant Extracts for Pesticidal Properties and HPLC-Based Identification of Active Compounds

1
Division of Pharmaceutical Biology, Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, CH-4056 Basel, Switzerland.
2
CIFLORPAN, College of Pharmacy, University of Panama, Apartado 0824-00172, Panama, Republic of Panama.
3
BASF SE, Carl-Bosch-Strasse 38, D-67056 Ludwigshafen, Germany.
*
Author to whom correspondence should be addressed.
Received: 17 October 2014 / Accepted: 11 December 2014 / Published: 11 December 2014
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Abstract

A library of 600 taxonomically diverse Panamanian plant extracts was screened for fungicidal, insecticidal, and herbicidal activities. A total of 19 active extracts were submitted to HPLC-based activity profiling, and extracts of Bocconia frutescens, Miconia affinis, Myrcia splendens, Combretum aff. laxum, and Erythroxylum macrophyllum were selected for the isolation of compounds. Chelerythrine (2), macarpine (3), dihydrosanguinarine (5), and arjunolic acid (8) showed moderate-to-good fungicidal activity. Myricetin-3-O-(6''-O-galloyl)-β-galactopyranoside (13) showed moderate insecticidal activity, but no compound with herbicidal activity was identified.
Keywords: Panamanian plant extracts; HPLC-based activity profiling; Fungicide; Insecticide; Herbicide Panamanian plant extracts; HPLC-based activity profiling; Fungicide; Insecticide; Herbicide
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

GULDBRANDSEN, N.; DE MIERI, M.; GUPTA, M.; SEISER, T.; WIEBE, C.; DICKHAUT, J.; REINGRUBER, R.; SORGENFREI, O.; HAMBURGER, M. Screening of Panamanian Plant Extracts for Pesticidal Properties and HPLC-Based Identification of Active Compounds. Sci. Pharm. 2015, 83, 353-367.

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