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Sci. Pharm. 2010, 78(3), 706; doi:10.3797/scipharm.cespt.8.PPAT17

Multidisciplinary Approach on Characterizing Composites of Vinpocetine and Crospovidone Obtained by Solid State Activation

1
Department of Pharmaceutical Sciences, University of Trieste, Trieste, Italy
2
Department of Chemical Engineering, University of Trieste, Trieste, Italy
3
Department of Pharmaceutical Sciences, University of Padua, Padua, Italy
4
Slovenian NMR Centre, National Institute of Chemistry, Ljubljana, Slovenia
*
Author to whom correspondence should be addressed.
Received: 12 July 2010 / Accepted: 12 July 2010 / Published: 12 July 2010
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Abstract

The poorly-soluble Vinpocetine was successfully coground with micronized crospovidone in a planetary mill, which allowed an enhancement of bioavailability through a solid-state activation. [...]
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

HASA, D.; VOINOVICH, D.; PERISSUTTI, B.; BONIFACIO, A.; GRASSI, M.; FRANCESCHINIS, E.; DALL’ACQUA, S.; SPEH, M.; PLAVEC, J. Multidisciplinary Approach on Characterizing Composites of Vinpocetine and Crospovidone Obtained by Solid State Activation. Sci. Pharm. 2010, 78, 706.

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