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Sci. Pharm. 2010, 78(3), 694; doi:10.3797/scipharm.cespt.8.PPAT05

Pharmaceutical Powder Compaction and Dissolution Analytics by Laboratory Small and Wide Angle X-Ray Scattering (SWAXS)

1
Research Center Pharmaceutical Engineering GmbH, Graz, Austria
2
Hecus X-Ray Systems GmbH, Graz, Austria
3
Institute of Biophysics and Nanosystems Research, Austrian Academy of Sciences, Graz, Austria
4
G.L. Pharma GmbH, Lannach, Austria
5
Institute for Process and Particle Engineering (IPPE), Graz University of Technology, Graz, Austria
*
Author to whom correspondence should be addressed.
Received: 12 July 2010 / Accepted: 12 July 2010 / Published: 12 July 2010
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Abstract

We investigate the compaction behavior of the most usual pharmaceutical excipients mixture (placebo) contained lactose monohydrate (LmH), microcrystalline cellulose (MCC), silicum dioxyd (SiO2) and magnesium stearate (MgSt) with combined small- and wide-angle X-ray scattering (SWAXS). [...]
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

HODZIC, A.; KRIECHBAUM, M.; TRITTHART, W.; REITER, F.; FRASER, S.; KHINAST, J.G.; LAGGNER, P. Pharmaceutical Powder Compaction and Dissolution Analytics by Laboratory Small and Wide Angle X-Ray Scattering (SWAXS). Sci. Pharm. 2010, 78, 694.

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