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Sci. Pharm.
Volume 78
Issue 1
10.3797/scipharm.0910-16
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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Article

Different Spontaneous Pulmonary Metastasis Inhibitions against Lewis Lung Carcinoma in Mice by Bisdioxopiperazine Compounds of Different Treatment Schedules

by
Da-Yong LU
1,*,
Fu-Geng WU
2,
Zu-Ming ZHEN
2,
Ting-Ren LU
3,
Hong-Ying WU
3,
Jin-Yu CHE
1 and
Bin XU
2
1
Shanghai University, Shanghai 200444, PR China
2
Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, PR China
3
College of Sciences, Shanghai University, Shanghai 200444, PR China
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2010, 78(1), 13-20; https://doi.org/10.3797/scipharm.0910-16
Submission received: 25 October 2009 / Accepted: 28 December 2009 / Published: 29 December 2009
Versions Notes

Abstract

Spontaneous neoplasm metastasis, a fatalist pathological feature of cancer, is a long-evolving, multi-steps process that can now only be treated or controlled by drugs or immuno-modulators. As we have previously hypothesized, each drug or immuno-modulator might act differently within various stages of a metastasis. Therefore any researches helping to determine these differences will be beneficial for updating therapeutics for metastasis. In this work, we have testified this hypothesis by using a series of well-known anti-metastatic agents – Bisdioxopiperazine compounds.
Keywords: Neoplasm metastasis; Bisdioxopiperazine compounds; Cancer chemotherapy; Probimane; Razoxane Neoplasm metastasis; Bisdioxopiperazine compounds; Cancer chemotherapy; Probimane; Razoxane

Share and Cite

MDPI and ACS Style

LU, D.-Y.; WU, F.-G.; ZHEN, Z.-M.; LU, T.-R.; WU, H.-Y.; CHE, J.-Y.; XU, B. Different Spontaneous Pulmonary Metastasis Inhibitions against Lewis Lung Carcinoma in Mice by Bisdioxopiperazine Compounds of Different Treatment Schedules. Sci. Pharm. 2010, 78, 13-20. https://doi.org/10.3797/scipharm.0910-16

AMA Style

LU D-Y, WU F-G, ZHEN Z-M, LU T-R, WU H-Y, CHE J-Y, XU B. Different Spontaneous Pulmonary Metastasis Inhibitions against Lewis Lung Carcinoma in Mice by Bisdioxopiperazine Compounds of Different Treatment Schedules. Scientia Pharmaceutica. 2010; 78(1):13-20. https://doi.org/10.3797/scipharm.0910-16

Chicago/Turabian Style

LU, Da-Yong, Fu-Geng WU, Zu-Ming ZHEN, Ting-Ren LU, Hong-Ying WU, Jin-Yu CHE, and Bin XU. 2010. "Different Spontaneous Pulmonary Metastasis Inhibitions against Lewis Lung Carcinoma in Mice by Bisdioxopiperazine Compounds of Different Treatment Schedules" Scientia Pharmaceutica 78, no. 1: 13-20. https://doi.org/10.3797/scipharm.0910-16

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