Next Article in Journal
Pluronic® F-68 Enhances the Nanoparticle-Cell Interaction
Previous Article in Journal
Cyclodextrins as Natural Co-Stabilising Agents in Submicron Emulsions
Article Menu

Article Versions

Export Article

Open AccessAbstract
Sci. Pharm. 2009, 77(Short Lectures (SL)), 178; doi:10.3797/scipharm.oephg.21.SL-11 (registering DOI)

An Acoustically-Driven Biochip: Particle-Cell In-teractions Under Physiological Flow Conditions

Dept. of Pharm. Technology& Biopharmaceutics, University of Vienna, Althanstr. 14, 1090 Vienna, Austria
Biological Physics Group, University Augsburg, Universitätsstr. 1, 86159, Augsburg, Germany
Author to whom correspondence should be addressed.
Received: 16 April 2009 / Accepted: 16 April 2009 / Published: 16 April 2009
Download PDF [329 KB, uploaded 11 May 2017]


Introduction: The interaction of particulate drug carriers with cells has generally been assessed in stationary microplate assays. These setups fail to reflect the flow conditions in vivo which generate substantial hydrodynamic drag forces [1]. In order to address this shortcoming, a microfluidic biochip with the capability of imitating a wide range of shear rates and pulsation modes has been developed. This device, which is based on an incorporated surface acoustic wave pump, was used to study the interaction of targeted microparticles with epithelial cells under flow conditions.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

FILLAFER, C.; RATZINGER, G.; NEUMANN, J.; DISSAUER, S.; WIRTH, M.; GABOR, F.; SCHNEIDER, M. An Acoustically-Driven Biochip: Particle-Cell In-teractions Under Physiological Flow Conditions. Sci. Pharm. 2009, 77, 178.

Show more citation formats Show less citations formats

Article Metrics

Article Access Statistics



[Return to top]
Sci. Pharm. EISSN 2218-0532 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top