Next Article in Journal
Pluronic® F-68 Enhances the Nanoparticle-Cell Interaction
Previous Article in Journal
Cyclodextrins as Natural Co-Stabilising Agents in Submicron Emulsions
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Sci. Pharm.
Volume 77
Issue 6
10.3797/scipharm.oephg.21.SL-11
scipharm-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles thumb_up
...
Endorse textsms
...
Comment
Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Abstract

An Acoustically-Driven Biochip: Particle-Cell In-teractions Under Physiological Flow Conditions

by
C. FILLAFER
1,*,
G. RATZINGER
1,
J. NEUMANN
2,
S. DISSAUER
1,
M. WIRTH
1,
F. GABOR
1 and
M. SCHNEIDER
2
1
Dept. of Pharm. Technology& Biopharmaceutics, University of Vienna, Althanstr. 14, 1090 Vienna, Austria
2
Biological Physics Group, University Augsburg, Universitätsstr. 1, 86159, Augsburg, Germany
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2009, 77(6), 178; https://doi.org/10.3797/scipharm.oephg.21.SL-11
Submission received: 16 April 2009 / Accepted: 16 April 2009 / Published: 16 April 2009
Versions Notes

Abstract

Introduction: The interaction of particulate drug carriers with cells has generally been assessed in stationary microplate assays. These setups fail to reflect the flow conditions in vivo which generate substantial hydrodynamic drag forces [1]. In order to address this shortcoming, a microfluidic biochip with the capability of imitating a wide range of shear rates and pulsation modes has been developed. This device, which is based on an incorporated surface acoustic wave pump, was used to study the interaction of targeted microparticles with epithelial cells under flow conditions.

Share and Cite

MDPI and ACS Style

FILLAFER, C.; RATZINGER, G.; NEUMANN, J.; DISSAUER, S.; WIRTH, M.; GABOR, F.; SCHNEIDER, M. An Acoustically-Driven Biochip: Particle-Cell In-teractions Under Physiological Flow Conditions. Sci. Pharm. 2009, 77, 178. https://doi.org/10.3797/scipharm.oephg.21.SL-11

AMA Style

FILLAFER C, RATZINGER G, NEUMANN J, DISSAUER S, WIRTH M, GABOR F, SCHNEIDER M. An Acoustically-Driven Biochip: Particle-Cell In-teractions Under Physiological Flow Conditions. Scientia Pharmaceutica. 2009; 77(Short Lectures (SL)):178. https://doi.org/10.3797/scipharm.oephg.21.SL-11

Chicago/Turabian Style

FILLAFER, C., G. RATZINGER, J. NEUMANN, S. DISSAUER, M. WIRTH, F. GABOR, and M. SCHNEIDER. 2009. "An Acoustically-Driven Biochip: Particle-Cell In-teractions Under Physiological Flow Conditions" Scientia Pharmaceutica 77, Short Lectures (SL): 178. https://doi.org/10.3797/scipharm.oephg.21.SL-11

Article Metrics

Back to TopTop