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Sci. Pharm. 2009, 77(Short Lectures (SL)), 173; doi:10.3797/scipharm.oephg.21.SL-06 (registering DOI)

LC-MS-MS Can Distinguish Between Toxic and Non-Toxic Pyrrolizidine Alkaloids in Plants

Phytomedicine Programme, University of Pretoria, Private Bag X04, Onderstepoort, 0110 South Africa
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Received: 16 April 2009 / Accepted: 16 April 2009 / Published: 16 April 2009
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Abstract

Several plants including medicinal plants and weeds that contaminate food crops contain pyrrolizidine alkaloids (PA). In the case of medicinal plants not used regularly, a low level of PA can be accommodated, but because food is consumed over a long time the allowable levels must be much lower [1]. Maize and soybean farmers in South Africa suffer economic losses due to the presence of Crotalaria sphaerocarpa seed pods in crops by the implementation of current regulations [1]. Because many Crotalaria species contain toxic PAs, there is a limit on the quantity of seeds that are allowed in the grain. C. sphaerocarpa undoubtedly contains pyrrolizidine alkaloids but toxicity to animals could not be established in several unpublished trials.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

ELOFF, J.N.; RÖSEMANN, M. LC-MS-MS Can Distinguish Between Toxic and Non-Toxic Pyrrolizidine Alkaloids in Plants. Sci. Pharm. 2009, 77, 173.

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