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Sci. Pharm. 2006, 74(1), 21-30; doi:10.3797/scipharm.2006.74.21 (registering DOI)

Investigation of the Direct Effects of the Alcoholic Extract of Elaeagnus angustifolia L. (Elaeagnaceae) on Dispersed Intestinal Smooth Muscle Cells of Guinea Pig

1
Department of Physiology and Biochemistry, Faculty of Medicine, University of Jordan
2
Pharmaceutical 2Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Jordan, Queen Rania Street, 11942 Amman-Jordan
*
Author to whom correspondence should be addressed.
Received: 3 October 2005 / Accepted: 9 January 2006 / Published: 1 March 2006
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Abstract

The effect of the ethanolic extract of Elaeagnus angustifolia was tested on dispersed smooth muscle cells (SMC) of the guinea pigs. A slight contractile response was observed when SMC were treated with low concentrations of the extract. Pre-treatment of the SMC with ethanolic extract of E. angustifolia caused concentration dependent inhibition of acetylcholine-induced contractions of the SMC.
Keywords: Elaeagnus angustifolia; dispersed smooth muscle cells; guinea pigs; acetylcholine Elaeagnus angustifolia; dispersed smooth muscle cells; guinea pigs; acetylcholine
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Mohammed, F.I.; Al-Essa, M.K.; Shafagoj, Y.A.; Afifi, F.U. Investigation of the Direct Effects of the Alcoholic Extract of Elaeagnus angustifolia L. (Elaeagnaceae) on Dispersed Intestinal Smooth Muscle Cells of Guinea Pig. Sci. Pharm. 2006, 74, 21-30.

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