Next Article in Journal
NPPD: A Protein-Protein Docking Scoring Function Based on Dyadic Differences in Networks of Hydrophobic and Hydrophilic Amino Acid Residues
Previous Article in Journal
Modulation of Group I Ribozyme Activity by Cationic Porphyrins
Article Menu

Export Article

Open AccessReview
Biology 2015, 4(2), 264-281; doi:10.3390/biology4020264

A Multi-Functional Tubulovesicular Network as the Ancestral Eukaryotic Endomembrane System

Centro Andaluz de Biologia del Desarollo (CABD), Universidad Pablo de Olavide, Carretera de Utrera km 1, Seville 41013, Spain
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Academic Editor: Chris O'Callaghan
Received: 25 November 2014 / Accepted: 3 March 2015 / Published: 24 March 2015
View Full-Text   |   Download PDF [540 KB, uploaded 24 March 2015]   |  

Abstract

The origin of the eukaryotic endomembrane system is still the subject of much speculation. We argue that the combination of two recent hypotheses addressing the eukaryotic endomembrane’s early evolution supports the possibility that the ancestral membranes were organised as a multi-functional tubulovesicular network. One of the potential selective advantages provided by this organisation was the capacity to perform endocytosis. This possibility is illustrated by membrane organisations observed in current organisms in the three domains of life. Based on this, we propose a coherent model of autogenous eukaryotic endomembrane system evolution in which mitochondria are involved at a late stage. View Full-Text
Keywords: Eukaryogenesis; membrane system; evolution; hypothesis Eukaryogenesis; membrane system; evolution; hypothesis
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

González-Sánchez, J.C.; Costa, R.; Devos, D.P. A Multi-Functional Tubulovesicular Network as the Ancestral Eukaryotic Endomembrane System. Biology 2015, 4, 264-281.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Biology EISSN 2079-7737 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top