Enhanced Macrophage Tribbles-1 Expression in Murine Experimental Atherosclerosis
Abstract
:1. Introduction
2. Results and Discussion
2.1. Trb 1 Expression in Mouse Atherosclerotic Lesions
2.2. Trb2 Expression in Mouse Atherosclerotic Lesions
2.3. Trb3 Expression in Mouse Atherosclerotic Lesions
2.4. Expression of Trbs in Mouse Atherosclerotic Lesions in the Absence of IL-1 Signalling
2.5. Tribbles-1 is a Negative Regulator of IL-6 Production and its’ Expression is Up-Regulated by IL-1 in Macrophages in vitro
3. Discussion
4. Experimental Section
4.1. Animals
4.2. Cell Culture
4.3. Western Blot, ELISA
4.4. Immunohistochemistry
4.5. Analysis of Trb Expression in Atherosclerotic Lesions
5. Conclusions
Acknowledgments
References and Notes
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Sung, H.Y.; Francis, S.E.; Arnold, N.D.; Holland, K.; Ernst, V.; Angyal, A.; Kiss-Toth, E. Enhanced Macrophage Tribbles-1 Expression in Murine Experimental Atherosclerosis. Biology 2012, 1, 43-57. https://doi.org/10.3390/biology1010043
Sung HY, Francis SE, Arnold ND, Holland K, Ernst V, Angyal A, Kiss-Toth E. Enhanced Macrophage Tribbles-1 Expression in Murine Experimental Atherosclerosis. Biology. 2012; 1(1):43-57. https://doi.org/10.3390/biology1010043
Chicago/Turabian StyleSung, Hye Youn, Sheila E. Francis, Nadine D. Arnold, Karen Holland, Vanessa Ernst, Adrienn Angyal, and Endre Kiss-Toth. 2012. "Enhanced Macrophage Tribbles-1 Expression in Murine Experimental Atherosclerosis" Biology 1, no. 1: 43-57. https://doi.org/10.3390/biology1010043