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Antibiotics 2018, 7(2), 33; https://doi.org/10.3390/antibiotics7020033

The Cellular Mechanisms that Ensure an Efficient Secretion in Streptomyces

Departamento de Biotecnología Microbiana, Centro Nacional de Biotecnología (CNB-CSIC), c/Darwin 3, 28049 Madrid, Spain
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Received: 27 February 2018 / Revised: 10 April 2018 / Accepted: 11 April 2018 / Published: 14 April 2018
(This article belongs to the Special Issue Actinomycetes: The Antibiotics Producers)
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Abstract

Gram-positive soil bacteria included in the genus Streptomyces produce a large variety of secondary metabolites in addition to extracellular hydrolytic enzymes. From the industrial and commercial viewpoints, the S. lividans strain has generated greater interest as a host bacterium for the overproduction of homologous and heterologous hydrolytic enzymes as an industrial application, which has considerably increased scientific interest in the characterization of secretion routes in this bacterium. This review will focus on the secretion machinery in S. lividans. View Full-Text
Keywords: Streptomyces lividans; secretion pathways; secretory proteins; signal peptides Streptomyces lividans; secretion pathways; secretory proteins; signal peptides
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Gullón, S.; Mellado, R.P. The Cellular Mechanisms that Ensure an Efficient Secretion in Streptomyces. Antibiotics 2018, 7, 33.

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