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Antibiotics 2015, 4(2), 198-215; doi:10.3390/antibiotics4020198

The Antimicrobial Stewardship Approach to Combating Clostridium Difficile

1
College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60612, USA
2
College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Yung-Fu Chang
Received: 6 May 2015 / Revised: 10 June 2015 / Accepted: 15 June 2015 / Published: 17 June 2015
(This article belongs to the Special Issue Clostridium difficile Infection)
View Full-Text   |   Download PDF [487 KB, uploaded 17 June 2015]   |  

Abstract

Clostridium difficile remains a major public health threat and continues to contribute to excess morbidity, mortality and healthcare costs. Antimicrobial stewardship programs have demonstrated success in combating C. difficile, primarily through antibiotic restrictive strategies. As the incidence and prevalence of C. difficile associate disease continues to increase both in the hospital and community setting, additional stewardship approaches are needed. This manuscript reviews stewardship interventions that have been successful against C. difficile associated disease and proposes future tactics that antimicrobial stewardship programs may employ to develop a more global approach to combat this difficult pathogen. View Full-Text
Keywords: antimicrobial stewardship; Clostridium difficile; restriction; diarrhea; rapid diagnostics; treatment; infection control antimicrobial stewardship; Clostridium difficile; restriction; diarrhea; rapid diagnostics; treatment; infection control
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Wenzler, E.; Mulugeta, S.G.; Danziger, L.H. The Antimicrobial Stewardship Approach to Combating Clostridium Difficile. Antibiotics 2015, 4, 198-215.

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