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Biosensors 2016, 6(3), 39; doi:10.3390/bios6030039

Electrochemical, Electrochemiluminescence, and Photoelectrochemical Aptamer-Based Nanostructured Sensors for Biomarker Analysis

Department of Chemistry “Ugo Schiff”, University of Florence, Via della Lastruccia 3, 50019 Sesto Fiorentino (FI), Italy
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Author to whom correspondence should be addressed.
Academic Editor: Jeff D. Newman
Received: 10 June 2016 / Revised: 12 July 2016 / Accepted: 27 July 2016 / Published: 2 August 2016
(This article belongs to the Special Issue Aptamer Sensors)
View Full-Text   |   Download PDF [1174 KB, uploaded 2 August 2016]   |  

Abstract

Aptamer-based sensors have been intensively investigated as potential analytical tools in clinical analysis providing the desired portability, fast response, sensitivity, and specificity, in addition to lower cost and simplicity versus conventional methods. The aim of this review, without pretending to be exhaustive, is to give the readers an overview of recent important achievements about electrochemical, electrochemiluminescence, and photoelectrochemical aptasensors for the protein biomarker determination, mainly cancer related biomarkers, by selected recent publications. Special emphasis is placed on nanostructured-based aptasensors, which show a substantial improvement of the analytical performances. View Full-Text
Keywords: aptamer; biosensor; electrochemical; electrochemiluminescent; photoelectrochemical; biomarker; nanomaterial aptamer; biosensor; electrochemical; electrochemiluminescent; photoelectrochemical; biomarker; nanomaterial
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Ravalli, A.; Voccia, D.; Palchetti, I.; Marrazza, G. Electrochemical, Electrochemiluminescence, and Photoelectrochemical Aptamer-Based Nanostructured Sensors for Biomarker Analysis. Biosensors 2016, 6, 39.

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