Biosensors 2012, 2(2), 114-126; doi:10.3390/bios2020114
Article

Optical Gratings Coated with Thin Si3N4 Layer for Efficient Immunosensing by Optical Waveguide Lightmode Spectroscopy

Lorena Diéguez 1,2,†,* email, David Caballero 1,2,3,‡ email, Josep Calderer 4 email, Mauricio Moreno 1 email, Elena Martínez 2,3 email and Josep Samitier 1,2,3 email
1 Department of Electronics, University of Barcelona, C/Martí i Franquès 1, Barcelona, ES 08028, Spain 2 Nanobioengineering Group, Institute for Bioengineering of Catalonia (IBEC), C/Baldiri Reixac 10-12, Barcelona, ES 08028, Spain 3 Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), C/María de Luna 11, Edificio CEEI, Zaragoza, ES 50018, Spain 4 Electronic Engineering Department, Universitat Politècnica de Catalunya, Campus Nord, Barcelona, ES 08034, Spain † Current Address: Ian Wark Research Institute (IWRI), University of South Australia, Mawson Lakes Boulevard, Mawson Lakes, SA 5095, Australia ‡ Current Address: Institut de Science et d’Ingénierie Supramoléculaires (ISIS), Université de Strasbourg, 8 allée Gaspard Monge, BP 70028, Strasbourg, Cedex, FR 67083, France
* Author to whom correspondence should be addressed.
Received: 1 February 2012; in revised form: 14 March 2012 / Accepted: 5 April 2012 / Published: 10 April 2012
PDF Full-text Download PDF Full-Text [573 KB, uploaded 10 April 2012 11:31 CEST]
Abstract: New silicon nitride coated optical gratings were tested by means of Optical Waveguide Lightmode Spectroscopy (OWLS). A thin layer of 10 nm of transparent silicon nitride was deposited on commercial optical gratings by means of sputtering. The quality of the layer was tested by x-ray photoelectron spectroscopy and atomic force microscopy. As a proof of concept, the sensors were successfully tested with OWLS by monitoring the concentration dependence on the detection of an antibody-protein pair. The potential of the Si3N4 as functional layer in a real-time biosensor opens new ways for the integration of optical waveguides with microelectronics.
Keywords: silicon nitride; optical gratings; waveguide; biosensor

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Diéguez, L.; Caballero, D.; Calderer, J.; Moreno, M.; Martínez, E.; Samitier, J. Optical Gratings Coated with Thin Si3N4 Layer for Efficient Immunosensing by Optical Waveguide Lightmode Spectroscopy. Biosensors 2012, 2, 114-126.

AMA Style

Diéguez L, Caballero D, Calderer J, Moreno M, Martínez E, Samitier J. Optical Gratings Coated with Thin Si3N4 Layer for Efficient Immunosensing by Optical Waveguide Lightmode Spectroscopy. Biosensors. 2012; 2(2):114-126.

Chicago/Turabian Style

Diéguez, Lorena; Caballero, David; Calderer, Josep; Moreno, Mauricio; Martínez, Elena; Samitier, Josep. 2012. "Optical Gratings Coated with Thin Si3N4 Layer for Efficient Immunosensing by Optical Waveguide Lightmode Spectroscopy." Biosensors 2, no. 2: 114-126.

Biosensors EISSN 2079-6374 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert