Next Article in Journal
Microfabricated Electrochemical Cell-Based Biosensors for Analysis of Living Cells In Vitro
Previous Article in Journal
Enzyme-Gelatin Electrochemical Biosensors: Scaling Down
Biosensors 2012, 2(2), 114-126; doi:10.3390/bios2020114
Article

Optical Gratings Coated with Thin Si3N4 Layer for Efficient Immunosensing by Optical Waveguide Lightmode Spectroscopy

1,2,†,* , 1,2,3,‡
,
4
,
1
,
2,3
 and
1,2,3
1 Department of Electronics, University of Barcelona, C/Martí i Franquès 1, Barcelona, ES 08028, Spain 2 Nanobioengineering Group, Institute for Bioengineering of Catalonia (IBEC), C/Baldiri Reixac 10-12, Barcelona, ES 08028, Spain 3 Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), C/María de Luna 11, Edificio CEEI, Zaragoza, ES 50018, Spain 4 Electronic Engineering Department, Universitat Politècnica de Catalunya, Campus Nord, Barcelona, ES 08034, Spain Current Address: Ian Wark Research Institute (IWRI), University of South Australia, Mawson Lakes Boulevard, Mawson Lakes, SA 5095, Australia Current Address: Institut de Science et d’Ingénierie Supramoléculaires (ISIS), Université de Strasbourg, 8 allée Gaspard Monge, BP 70028, Strasbourg, Cedex, FR 67083, France
* Author to whom correspondence should be addressed.
Received: 1 February 2012 / Revised: 14 March 2012 / Accepted: 5 April 2012 / Published: 10 April 2012
View Full-Text   |   Download PDF [573 KB, uploaded 10 April 2012]   |   Browse Figures

Abstract

New silicon nitride coated optical gratings were tested by means of Optical Waveguide Lightmode Spectroscopy (OWLS). A thin layer of 10 nm of transparent silicon nitride was deposited on commercial optical gratings by means of sputtering. The quality of the layer was tested by x-ray photoelectron spectroscopy and atomic force microscopy. As a proof of concept, the sensors were successfully tested with OWLS by monitoring the concentration dependence on the detection of an antibody-protein pair. The potential of the Si3N4 as functional layer in a real-time biosensor opens new ways for the integration of optical waveguides with microelectronics.
Keywords: silicon nitride; optical gratings; waveguide; biosensor silicon nitride; optical gratings; waveguide; biosensor
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
SciFeed

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
RIS
MDPI and ACS Style

Diéguez, L.; Caballero, D.; Calderer, J.; Moreno, M.; Martínez, E.; Samitier, J. Optical Gratings Coated with Thin Si3N4 Layer for Efficient Immunosensing by Optical Waveguide Lightmode Spectroscopy. Biosensors 2012, 2, 114-126.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

[Return to top]
Biosensors EISSN 2079-6374 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert