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Nanomaterials 2015, 5(1), 63-89; doi:10.3390/nano5010063

Magnetic Properties of Magnetic Nanoparticles for Efficient Hyperthermia

1
Department of Physics, United Arab Emirates University, Al-Ain 15551, United Arab Emirates
2
Department of Mechanical Engineering, United Arab Emirates University, Al-Ain 15555, United Arab Emirates
3
Center for Research Excellence in Nanobiosciences, University of North Carolina at Greensboro, Greensboro, NC 27412, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Thomas Nann
Received: 15 November 2014 / Accepted: 30 December 2014 / Published: 9 January 2015
View Full-Text   |   Download PDF [309 KB, uploaded 9 January 2015]

Abstract

Localized magnetic hyperthermia using magnetic nanoparticles (MNPs) under the application of small magnetic fields is a promising tool for treating small or deep-seated tumors. For this method to be applicable, the amount of MNPs used should be minimized. Hence, it is essential to enhance the power dissipation or heating efficiency of MNPs. Several factors influence the heating efficiency of MNPs, such as the amplitude and frequency of the applied magnetic field and the structural and magnetic properties of MNPs. We discuss some of the physics principles for effective heating of MNPs focusing on the role of surface anisotropy, interface exchange anisotropy and dipolar interactions. Basic magnetic properties of MNPs such as their superparamagnetic behavior, are briefly reviewed. The influence of temperature on anisotropy and magnetization of MNPs is discussed. Recent development in self-regulated hyperthermia is briefly discussed. Some physical and practical limitations of using MNPs in magnetic hyperthermia are also briefly discussed. View Full-Text
Keywords: magnetic nanoparticles (MNPs); hyperthermia; power dissipation; curie temperature; anisotropy magnetic nanoparticles (MNPs); hyperthermia; power dissipation; curie temperature; anisotropy
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Obaidat, I.M.; Issa, B.; Haik, Y. Magnetic Properties of Magnetic Nanoparticles for Efficient Hyperthermia. Nanomaterials 2015, 5, 63-89.

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