Next Article in Journal
Eicosopentaneoic Acid and Other Free Fatty Acid Receptor Agonists Inhibit Lysophosphatidic Acid- and Epidermal Growth Factor-Induced Proliferation of Human Breast Cancer Cells
Previous Article in Journal
Acknowledgement to Reviewers of Journal of Clinical Medicine in 2015
Article Menu

Export Article

Open AccessCase Report
J. Clin. Med. 2016, 5(2), 14; doi:10.3390/jcm5020014

Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and Neurorehabilitation

1
Medical Centre Foltra, Travesía de Montouto 24, Teo 15886, Spain
2
Department of Physiology, School of Medicine, University of Santiago de Compostela, Santiago de Compostela 15710, Spain
*
Author to whom correspondence should be addressed.
Academic Editor: Nuri B. Farber
Received: 28 November 2015 / Revised: 16 January 2016 / Accepted: 19 January 2016 / Published: 26 January 2016
View Full-Text   |   Download PDF [1207 KB, uploaded 3 February 2016]   |  

Abstract

Background—To describe the results obtained after treating a non growth hormone-deficient 10-year-old girl who suffered asphyxia during delivery, resulting in important cognitive deficits, with growth hormone (GH) and neurorehabilitation. Methods—GH was administered (mg/day) at doses of 0.5 over three months followed by 0.9, every two weeks over three months, and then alternating 1.2 three days/week and 0.3 two days/week. Neurorehabilitation consisted of daily sessions of neurostimulation, speech therapy, occupational therapy and auditive stimulation. Treatment lasted nine months. Results—Scores obtained in all the areas treated showed that, at discharge, the patient clearly increased her cognitive abilities, memory and language competence index; her intelligence quotient score increased from 51 to 80, and the index of functional independence measure reached a value of 120 over 126 (maximal value). Conclusions—This case suggests that GH administration may play a role in improving cognitive deficits during neurorehabilitation in children with brain damage suffered during delivery. This agrees with the known effects of GH on cognition. View Full-Text
Keywords: growth hormone; neurorehabilitation; brain plasticity; cognitive functions; memory; natal asphyxia growth hormone; neurorehabilitation; brain plasticity; cognitive functions; memory; natal asphyxia
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Devesa, J.; Lema, H.; Zas, E.; Munín, B.; Taboada, P.; Devesa, P. Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and Neurorehabilitation. J. Clin. Med. 2016, 5, 14.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
J. Clin. Med. EISSN 2077-0383 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top