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J. Clin. Med. 2014, 3(3), 865-882; doi:10.3390/jcm3030865

Screening and Invasive Testing in Twins

Department of Obstetrics and Gynecology, Prenatal and Preimplantation Genetic Diagnosis, Fetal Therapy, Ospedale Microcitemico, via Jenner, 09121 Cagliari, Italy
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Received: 8 April 2014 / Revised: 26 June 2014 / Accepted: 27 June 2014 / Published: 29 July 2014
(This article belongs to the Special Issue Prenatal Genetic Screening and Diagnosis-Part 2)
View Full-Text   |   Download PDF [244 KB, uploaded 29 July 2014]

Abstract

Prenatal screening and testing for trisomy 21 in twin pregnancies poses a number of challenges: the exact estimate of the a priori risk of trisomy 21, the choice of prenatal screening test and/or invasive techniques to employ for the diagnosis and the impact of the result on the options of treatment in case of discordant results within a twin pair or among multiples. These different aspects are discussed below while recognizing that many issues remain unresolved. View Full-Text
Keywords: twins; screening; invasive diagnosis; therapy twins; screening; invasive diagnosis; therapy
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Monni, G.; Iuculano, A.; Zoppi, M.A. Screening and Invasive Testing in Twins. J. Clin. Med. 2014, 3, 865-882.

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