J. Clin. Med. 2014, 3(3), 741-746; doi:10.3390/jcm3030741
Communication

Pregnancy Loss Following Amniocentesis or CVS Sampling—Time for a Reassessment of Risk

Received: 31 March 2014; in revised form: 24 May 2014 / Accepted: 29 May 2014 / Published: 8 July 2014
(This article belongs to the Special Issue Prenatal Genetic Screening and Diagnosis-Part 2)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Risk of procedure-related pregnancy loss is currently widely quoted in the UK as 1% for amniocentesis and 1.5% for chorionic villus sampling. Published data suggest that these risk figures are out of date and inaccurate, and that new guidelines are required for pre-test counseling. It is our opinion that accurate and evidence-based information concerning miscarriage risk is vital when counseling women, as exaggeration of this risk may deter women from testing, or cause unjustified remorse if a miscarriage ensues. It is also essential that health-care economists are aware of the up-to-date evidence on “procedure-related risk” when applying risk-benefit analysis to assess new technology for non-invasive screening.
Keywords: miscarriage; procedure-related pregnancy loss; amniocentesis; chorionic villus sampling (CVS); non-invasive prenatal testing; cell free fetal DNA
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MDPI and ACS Style

Ogilvie, C.; Akolekar, R. Pregnancy Loss Following Amniocentesis or CVS Sampling—Time for a Reassessment of Risk. J. Clin. Med. 2014, 3, 741-746.

AMA Style

Ogilvie C, Akolekar R. Pregnancy Loss Following Amniocentesis or CVS Sampling—Time for a Reassessment of Risk. Journal of Clinical Medicine. 2014; 3(3):741-746.

Chicago/Turabian Style

Ogilvie, Caroline; Akolekar, Ranjit. 2014. "Pregnancy Loss Following Amniocentesis or CVS Sampling—Time for a Reassessment of Risk." J. Clin. Med. 3, no. 3: 741-746.

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