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Membranes 2012, 2(1), 70-90; doi:10.3390/membranes2010070
Review

Development of Hydrogels and Biomimetic Regulators as Tissue Engineering Scaffolds

1,2,3
,
2,3,4,*  and 1,5,*
1 Department of Textile Sciences, Faculty of Human Ecology, University of Manitoba, Winnipeg, MB R3T 2N2, Canada 2 Department of Mechanical Engineering, University of Manitoba, Winnipeg, MB R3T 2N2, Canada 3 Manitoba Institute of Child Health, Winnipeg, MB R3E 3P5, Canada 4 Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, MB R3T 2N2, Canada 5 Department of Medical Microbiology, Faculty of Medicine, University of Manitoba, Winnipeg, MB R3T 2N2, Canada
* Authors to whom correspondence should be addressed.
Received: 26 December 2011 / Revised: 17 January 2012 / Accepted: 2 February 2012 / Published: 14 February 2012
(This article belongs to the Special Issue Membranes for Health and Environmental Applications)
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Abstract

This paper reviews major research and development issues relating to hydrogels as scaffolds for tissue engineering, the article starts with a brief introduction of tissue engineering and hydrogels as extracellular matrix mimics, followed by a description of the various types of hydrogels and preparation methods, before a discussion of the physical and chemical properties that are important to their application. There follows a short comment on the trends of future research and development. Throughout the discussion there is an emphasis on the genetic understanding of bone tissue engineering application.
Keywords: hydrogel; bone; tissue engineering hydrogel; bone; tissue engineering
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Shi, J.; Xing, M.M.Q.; Zhong, W. Development of Hydrogels and Biomimetic Regulators as Tissue Engineering Scaffolds. Membranes 2012, 2, 70-90.

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