Next Issue
Previous Issue

Table of Contents

Microarrays, Volume 1, Issue 3 (December 2012), Pages 107-124

  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
  • You may sign up for e-mail alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Readerexternal link to open them.
View options order results:
result details:
Displaying articles 1-1
Export citation of selected articles as:

Review

Open AccessReview Integrated Amplification Microarrays for Infectious Disease Diagnostics
Microarrays 2012, 1(3), 107-124; doi:10.3390/microarrays1030107
Received: 24 September 2012 / Revised: 31 October 2012 / Accepted: 7 November 2012 / Published: 9 November 2012
Cited by 2 | PDF Full-text (458 KB) | HTML Full-text | XML Full-text
Abstract
This overview describes microarray-based tests that combine solution-phase amplification chemistry and microarray hybridization within a single microfluidic chamber. The integrated biochemical approach improves microarray workflow for diagnostic applications by reducing the number of steps and minimizing the potential for sample or amplicon [...] Read more.
This overview describes microarray-based tests that combine solution-phase amplification chemistry and microarray hybridization within a single microfluidic chamber. The integrated biochemical approach improves microarray workflow for diagnostic applications by reducing the number of steps and minimizing the potential for sample or amplicon cross-contamination. Examples described herein illustrate a basic, integrated approach for DNA and RNA genomes, and a simple consumable architecture for incorporating wash steps while retaining an entirely closed system. It is anticipated that integrated microarray biochemistry will provide an opportunity to significantly reduce the complexity and cost of microarray consumables, equipment, and workflow, which in turn will enable a broader spectrum of users to exploit the intrinsic multiplexing power of microarrays for infectious disease diagnostics. Full article
(This article belongs to the Special Issue Feature Papers)

Journal Contact

MDPI AG
Microarrays Editorial Office
St. Alban-Anlage 66, 4052 Basel, Switzerland
microarrays@mdpi.com
Tel. +41 61 683 77 34
Fax: +41 61 302 89 18
Editorial Board
Contact Details Submit to Microarrays
Back to Top