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Open AccessBrief Report
Brain Sci. 2017, 7(4), 36; doi:10.3390/brainsci7040036

Brief Report: Using the Internet to Identify Persons with Cognitive Impairment for Participation in Clinical Trials

The Johns Hopkins University School of Medicine, Psychiatry and Behavioral Sciences, Division of Medical Psychology, The Johns Hopkins Hospital, 600 North Wolfe Street, Meyer 218, Baltimore, MD 21287-7218, USA
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Author to whom correspondence should be addressed.
Academic Editor: Andrea Loftus
Received: 10 February 2017 / Revised: 31 March 2017 / Accepted: 31 March 2017 / Published: 5 April 2017
(This article belongs to the Special Issue Risk Factors for Mild Cognitive Impairment (MCI))
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Abstract

Identifying, recruiting, and enrolling persons in clinical trials of dementia treatments is extremely difficult. One approach to first-wave screening of potential participants is the use of online assessment tools. Initial studies using the Dementia Risk Assessment (DRA)—which includes a previously validated recognition memory test—support the use of this self-administered assessment to identify individuals with “suspected MCI” or “suspected dementia.” In this study, we identified between 71 and 622 persons with suspected dementia and between 128 and 1653 persons with suspected mild cognitive impairment (depending on specific criteria) over the course of 22 months. Assessment tools that can inexpensively and easily identify individuals with higher than average risk for cognitive impairment can facilitate recruitment for large-scale clinical trials for dementia treatments. View Full-Text
Keywords: clinical trials; MCI; risk; dementia; Alzheimer’s; cognitive impairment; assessment clinical trials; MCI; risk; dementia; Alzheimer’s; cognitive impairment; assessment
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Morra, L.F.; Brandt, J. Brief Report: Using the Internet to Identify Persons with Cognitive Impairment for Participation in Clinical Trials. Brain Sci. 2017, 7, 36.

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