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Appl. Sci. 2018, 8(9), 1568; https://doi.org/10.3390/app8091568

A Single Simulation Platform for Hybrid Photoacoustic and RF-Acoustic Computed Tomography

1
Department of Electrical Engineering, The Pennsylvania State University, University Park, PA 16802, USA
2
Department of Biomedical Engineering, The Pennsylvania State University, University Park, PA 16802, USA
3
Penn State Hershey Cancer Institute, The Pennsylvania State University, Hershey, PA 17033, USA
*
Author to whom correspondence should be addressed.
Received: 3 July 2018 / Revised: 25 August 2018 / Accepted: 29 August 2018 / Published: 6 September 2018
(This article belongs to the Special Issue Photoacoustic Tomography (PAT))
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Abstract

In recent years, multimodal thermoacoustic imaging has demonstrated superior imaging quality compared to other emerging modalities. It provides functional and molecular information, arising due to electromagnetic absorption contrast, at ultrasonic resolution using inexpensive and non-ionizing imaging methods. The development of optical- as well as radio frequency (RF)-induced thermoacoustic imaging systems would benefit from reliable numerical simulations. To date, most numerical models use a combination of different software in order to model the hybrid thermoacoustic phenomenon. Here, we demonstrate the use of a single open source finite element software platform (ONELAB) for photo- and RF-acoustic computed tomography. The solutions of the optical diffusion equation, frequency domain Maxwell’s equations, and time-domain wave equation are used to solve the optical, electromagnetic, and acoustic propagation problems, respectively, in ONELAB. The results on a test homogeneous phantom and an approximate breast phantom confirm that ONELAB is a very effective software for both photo- and RF-acoustic simulations, and invaluable for developing new reconstruction algorithms and hardware systems. View Full-Text
Keywords: photoacoustic imaging; tomography; thermoacoustic; radio frequency photoacoustic imaging; tomography; thermoacoustic; radio frequency
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Fadden, C.; Kothapalli, S.-R. A Single Simulation Platform for Hybrid Photoacoustic and RF-Acoustic Computed Tomography. Appl. Sci. 2018, 8, 1568.

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