Can OCT Angiography Be Made a Quantitative Blood Measurement Tool?
Abstract
:Featured Application
Abstract
1. Introduction
2. OCTA Fundamentals
2.1. Hemodynamic Parameters
2.2. Light Scattering from Red Blood Cells
3. OCTA Signal
4. OCTA Algorithms
4.1. Intensity- or Amplitude-Based OCTA Algorithms
4.2. Phase-Based OCTA Algorithms
4.3. Complex Signal-Based OCTA Algorithms
4.4. Classification of Present OCTA Algorithms
5. OCTA Scanning Protocols
6. Empirical Validation of OCTA
7. OCTA Measurements of Hemodynamics
7.1. Flow Quantification
7.2. Hematocrit Quantification
8. Can OCTA Be Made a Quantitative Tool?
9. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Symbol | Meaning |
---|---|
Complex OCT signal/field | |
Amplitude of the OCT signal | |
Intensity of the OCT signal | |
Phase of the OCT signal | |
OCT field from one scatterer | |
Speckle variance | |
Correlation mapping OCT signal | |
Phase variance | |
Phase difference | |
Complex field difference | |
Complex differential variance | |
Autocorrelation function | |
Power spectral density |
Category | Classification |
---|---|
OCT signal | Field vs. Intensity/Amplitude vs. Phase |
Calculation | Variance/Difference vs. Correlation |
Averaging method | Temporal vs. Spatial vs. Spectral |
Normalization | Normalized vs. Non-normalized |
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Zhu, J.; Merkle, C.W.; Bernucci, M.T.; Chong, S.P.; Srinivasan, V.J. Can OCT Angiography Be Made a Quantitative Blood Measurement Tool? Appl. Sci. 2017, 7, 687. https://doi.org/10.3390/app7070687
Zhu J, Merkle CW, Bernucci MT, Chong SP, Srinivasan VJ. Can OCT Angiography Be Made a Quantitative Blood Measurement Tool? Applied Sciences. 2017; 7(7):687. https://doi.org/10.3390/app7070687
Chicago/Turabian StyleZhu, Jun, Conrad W. Merkle, Marcel T. Bernucci, Shau Poh Chong, and Vivek J. Srinivasan. 2017. "Can OCT Angiography Be Made a Quantitative Blood Measurement Tool?" Applied Sciences 7, no. 7: 687. https://doi.org/10.3390/app7070687